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Table 2 Specimen collection schedules

From: International prospective observational cohort study of Zika in infants and pregnancy (ZIP study): study protocol

Maternal specimen collection schedule
  First trimester < 14 weeksSecond Trimester < 28 weeks gestationThird Trimester 28 weeks and greaterDelivery: live birth or fetal loss6 weeks postpartum +/−  14 daysZika symptomatic visits
Screening & EntryMonthly visitsMonthly visitsMonthly visits
Serum, plasma, whole blood, urine, saliva, vaginal swabXXXXXXX
Breast milk    XX 
Amniotic fluid (if possible)  Only if amniocentesis was performed for clinical careX  
Cord blood (if possible)    X  
Placenta and fetal tissue if fetal loss (if possible)    X  
Infant specimen collection schedule
 Birth3 months6 months12 months
Urine, saliva, serumXXXX
Cerebrospinal fluid (remnant specimen)Only if collected for clinical careOnly if collected for clinical careOnly if collected for clinical careOnly if collected for clinical care