Table 2 Specimen collection schedules
Maternal specimen collection schedule | |||||||
First trimester < 14 weeks | Second Trimester < 28 weeks gestation | Third Trimester 28 weeks and greater | Delivery: live birth or fetal loss | 6 weeks postpartum +/− 14 days | Zika symptomatic visits | ||
Screening & Entry | Monthly visits | Monthly visits | Monthly visits | ||||
Serum, plasma, whole blood, urine, saliva, vaginal swab | X | X | X | X | X | X | X |
Breast milk | X | X | |||||
Amniotic fluid (if possible) | Only if amniocentesis was performed for clinical care | X | |||||
Cord blood (if possible) | X | ||||||
Placenta and fetal tissue if fetal loss (if possible) | X | ||||||
Infant specimen collection schedule | |||||||
Birth | 3 months | 6 months | 12 months | ||||
Urine, saliva, serum | X | X | X | X | |||
Cerebrospinal fluid (remnant specimen) | Only if collected for clinical care | Only if collected for clinical care | Only if collected for clinical care | Only if collected for clinical care | |||