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Table 2 live born neonatal brain injury detected by ultrasound between twin-twin transfusion syndrome (TTTS) patients with and without transient donor hydrops (TDH) after laser therapy

From: Predisposing factors and neonatal outcomes for twin-twin transfusion syndrome cases developing transient donor hydrops after fetoscopic laser coagulation: a case control study

  With TDH after laser therapy (n = 37) Without TDH after laser therapy (n = 172) p
Mild brain injury 1 (2.7%) 8 (4.7%) 1.0
Severe brain injury 1 (2.7%) 4 (2.3%) 1.0
Total brain injury 2 (5.4%) 11 (6.4%) 1.0
  1. Mild cerebral injury was defined as having lesions detected by cranial ultrasound scans with the presence of at least one of the following: intraventricular hemorrhage (IVH) grade I and II, lenticulostriate vasculopathy and subependymal pseudocysts
  2. Severe cerebral injury was defined as having at least one of the following: IVH grade III or grade IV, cystic periventriculoleukomalacia (PVL) grade II or more, porencephalic cysts, and ventricular dilatation. Ventricular dilatation was said to be present when the width of unilateral or both lateral ventricles exceeded the 97th percentile
  3. P values were generated by fisher’s exact test