Table 5 Haemodynamic effects of 5 U (8.3 μg) oxytocin given as the second injection at T2-T3 in women given placebo as the first injection
Variable | Oxytocin (PO group) N = 26 | |||
|---|---|---|---|---|
T2 value Mean ± SD Median (range) | T3 value Mean ± SD Median (range) | P a | Effect | |
MAP (mmHg) | 73 ± 8 74 (57, 87) | 71 ± 11 71 (51, 90) | 0.046 | BP decrease |
HR (bpm) | 66 ± 8 65 (53, 82) | 73 ± 10 72 (53, 88) | 0.001 | HR increase |
ECG ST index | 0.33 ± 0.21 0.30 (0.00, 0.80) | 0.18 ± 0.29 0.20 (− 0.40, 0.70) | 0.014 | ST decrease |
PH | 9.9 ± 3.3 9.5 (4.9, 16,0) | 11.0 ± 3.0 11.5 (5.5, 16.0) | 0.019 | Peripheral vasodilation |
ETc (ms) | 356 ± 55 371 (156, 404) | 367 ± 60 381 (179, 430) | 0.39 | No change |
EEI | 0.53 ± 0.13 0.51 (0.36, 0.83) | 0.50 ± 0.13 0.48 (0.33, 0.80) | 0.33 | No change |
EEI@75 | 0.61 ± 0.15 0.57 (0.41, 0.96) | 0.52 ± 0.15 0.52 (0.31, 0.84) | 0.33 | No change |
DI | 0.67 ± 0.14 0.66 (0.41, 0.99) | 0.58 ± 0.20 0.53 (0.26, 0.99) | 0.006 | Small-artery vasodilation |
DI@75 | 0.59 ± 0.15 0.61 (0.22, 0.88) | 0.56 ± 0.20 0.55 (0.12, 1.06) | 0.013 | Small-artery vasodilation |
b/a | −0.56 ± 0.08 − 0.55 (− 0.78, − 0.39) | − 0.56 ± 0.10 − 0.57 (− 0.74, − 0.35) | 0.056 | No change |
d/a | −0.23 ± 0.13 − 0.20 (− 0.76, − 0.08) | − 0.22 ± 0.09 − 0.21 (− 0.40, − 0.04) | 0.42 | No change |
AI | −0.25 ± 0.20 − 0.30 (− 0.50, 0.25) | −0.20 ± 0.19 − 0.20 (− 0.68, 0.05) | 0.15 | No change |