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Table 2 sFlt-1, PlGF and sFlt-1:PlGF ratios compared between controls and: (i) cases with a SGA infant; (ii) preeclampsia cases

From: Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

  Controls All SGA P SGA only P Preeclampsia P
sFlt-1 (pg/ml) 2446
[1795–3503]
2837
[1850–4250]
0.02 2620
[1835–4099]
0.10 4857
[3777–6941]
< 0.001
PlGF (pg/ml) 326.7
[173.1–675.4]
178.5
[106.4–404.8]
< 0.001 199.9
[118.1–448.6]
< 0.001 99.73
[61.99–158.6]
< 0.001
sFlt-1:PlGF ratio 7.11
[3.08–15.58]
14.24
[6.00–37.37]
< 0.001 13.00
[5.27–32.44]
< 0.001 54.25
[26.81–114.5]
< 0.001
  1. Data presented as median [25th–75th percentile]. “All SGA” = Cases with a SGA fetuses including cases with co-existent preeclampsia; “SGA only” = Cases with SGA fetuses with cases of co-existant preeclampisa excluded; pg/ml = picogram/millilitre, PlGF placental growth factor, sFlt-1 soluble fms-like tyrosine kinase-1, SGA small-for-gestational-age (birthweight <10th centile). For sFlt-1 and sFlt-1:PlGF ratio results n = 207 for controls, n = 102 for ‘All SGA’, n = 39 for ‘Preeclampsia’. For PlGF results n = 210 for controls, n = 104 for ‘All SGA’, and n = 39 for ‘Preeclampsia’