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Table 2 Comparisons of hemodynamic parameters between the groups and between successive points of measurement

From: Maternal cardiovascular hemodynamics in normotensive versus preeclamptic pregnancies: a prospective longitudinal study using a noninvasive cardiac system (NICaS™)

 

Control group

 

PET group

  

Median (25th–75th percentiles)

P value related to previous

Median (25th–75th percentiles)

P value related to previous

P value between groups

Before CS

N = 62

 

N = 17

   

 MAP (mmHg)

87.8 (82–94)

–

106 (87–110)

–

< 0.001a

 TPR (dyn × sec/cm5)

896.8 (802.7–1129.7)

–

1227 (1141–1527)

–

0.0042

 HR (beats/min)

85 (76–93)

–

75 (71–84)

–

NS

 SV (ml)

87.7 (74–100.6)

–

76.6 (69.4–96.8)

–

NS

 CO (l/min)

7.7 (6.3–8.6)

–

5.7 (5.3–7.7)

–

0.0331

After spinal anesthesia

N = 60

 

N = 12

–

 

 MAP (mmHg)

90 (81–101.3)

NS

120 (90.5–133)

0.0027

< 0.001a

 TPR (dyn × sec/cm5)

847.3 (703.5–1074.4)

NS

1477 (1154–1682)

NS

< 0.001a

 HR (beats/min)

96.5 (76.5–109)

< 0.001a

95.5 (79.5–111)

0.0033

NS

 SV (ml)

87.1 (76.1–104.3)

NS

76.9 (57.2–94.8)

NS

0.0254

 CO (l/min)

8.3 (6.9–10)

0.0075

6.6 (5.5–8.4)

NS

0.0107

Immediately post-delivery

N = 36

 

N = 13

  

 MAP (mmHg)

80.8 (70.5–91)

< 0.001a

103 (91–114)

0.0308

< 0.001a

 TPR (dyn × sec/cm5)

717.9 (558.3–897.3)

0.0339

1166 (972–1606)

NS

< 0.001a

 HR (beats/min)

91 (81.5–98.5)

NS

84 (77–91)

NS

NS

 SV (ml)

96.9 (89.6–110.5)

0.0048

78.3 (69.6–97)

NS

0.0102

 CO (l/min)

8.9 (7.2–11.3)

NS

7.1 (5.2–8.3)

NS

0.0054

After fascia closure

N = 31

 

N = 12

  

 MAP (mmHg)

86 (71.7–93.3)

NS

99.5 (87.5–106)

NS

0.0033

 TPR (dyn × sec/cm5)

802.8 (644.8–1115.4)

0.0273

2087 (1240–2671)

< 0.001a

< 0.001a

 HR (beats/min)

91 (81.5–100)

NS

80 (73–98)

NS

NS

 SV (ml)

94.7 (83.2–120.3)

NS

67.6 (43.6–75.2)

0.0039

< 0.001a

 CO (l/min)

8.4 (7–10.3)

NS

5 (3.4–6.3)

0.0083

< 0.001a

Within 24–36 h postpartum

N = 62

 

N = 16

  

 MAP (mmHg)

88 (84.3–92.7)

NS

97.5 (92.5–103)

NS

0.015

 TPR (dyn × sec/cm5)

1023.7 (863.5–1316.9)

NS

1326 (1211–1681)

< 0.001a

0.0021

 HR (beats/min)

84 (75–91)

NS

79.5 (71–89.5)

NS

NS

 SV (ml)

81.6 (67–94.5)

< 0.001a

73.4 (67.7–85.8)

NS

NS

 CO (l/min)

6.7 (5.7–8)

< 0.001a

5.5 (5.3–6.5)

NS

NS

Within 48–72 h postpartum

N = 59

 

N = 16

  

 MAP (mmHg)

88.7 (82.7–95.3)

NS

100.5 (95.5–104.5)

NS

< 0.001a

 TPR (dyn × sec/cm5)

1043.7 (926.5–1168.4)

NS

1261 (1028–1494)

NS

NS

 HR (beats/min)

83 (75–94)

NS

84 (72.5–99)

NS

NS

 SV (ml)

82.9 (69.5–98)

NS

79 (68.1–103)

NS

NS

 CO (l/min)

6.8 (6–7.8)

NS

6.7 (5.6–7.6)

NS

NS

  1. a Significance was also found after adjusted for multiple comparisons
  2. P- values are given when 0.001 < P < 0.05
  3. NS not significant, N number of women, CS cesarean section, MAP mean arterial pressure, TPR total peripheral resistance, HR heart rate, SV stroke volume, CO cardiac output
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