Table 3 Unadjusted and adjusted odds ratio for the development of gestational hypertension after exposure to antidepressant drugs during pregnancy in the primary analysis

 No exposure

98.08

 Exposure

1.92

1.99 (1.29–3.09)

.002

2.00 (1.28–3.13)

.002

 TCAs (N06AA)

16.51

1.61 (0.51–5.11)

.418

1.60 (0.50–5.09)

.429

 SSRIs (N06AB)

73.10

2.11 (1.30–3.45)

.003

2.07 (1.25–3.44)

.005

 MAOI (N06AF)

–

–

–

–

–

 RIMA (N06AG)

–

–

–

–

–

 Other (N06AX)

12.25

1.44 (0.35–5.90)

.611

1.43 (0.35–5.91)

.618

  ≤ 30

27.64

0.64 (0.16–2.57)

.524

0.68 (0.17–2.75)

.584

  ≥ 30

72.36

2.55 (1.61–4.02)

<.001

2.50 (1.55–3.99)

<.001

  ≤ 30

16.70

0.52 (0.07–3.74)

.516

1.28 (0.56–2.92)

.561

  ≥ 30

56.40

2.61 (1.57–4.35)

<.001

2.27 (1.44–3.60)

<.001

 0–10 weeks

93.88

2.14 (1.38–3.30)

.001

2.13 (1.36–3.34)

.001

 11–20 weeks

53.80

2.38 (1.38–4.10)

.002

2.36 (1.35–4.12)

.003

 0–10 weeks only

46,20

1.56 (0.77–3.17)

.220

1.59 (0.78–3.26)

.205

 Both periods (0–20 weeks)

47.68

2.71 (1.57–4.67)

<.001

2.66 (1.52–4.65)

.001

 15–19

1.69

–

–

–

–

 20–24

12.98

1.11 (0.15–8.16)

.919

–

–

 25–29

36.52

2.03 (0.89–4.65)

.093

–

–

 30–34

34.25

2.59 (1.35–4.98)

.004

–

–

 34–39

12.49

1.23 (0.38–3.95)

.731

–

–

 40+

2.07

1.26 (0.29–5.56)

.758

–

–