|
Did the trial address a clearly focused issue?
|
Yes
|
Yes
|
Yes
|
Yes
|
|
Was the assignment of patients to treatments randomised?
|
Yes
|
N (although described as randomised)
|
Yes
|
Can’t tell
|
|
Were all of the patients who entered the trial properly accounted for at its conclusion?
|
No
|
No
|
Yes
|
Yes
|
|
Were patients, health workers and study personnel ‘blind’ to treatment?
|
No
|
No (only patients were blinded)
|
Yes
|
No (able to differentiate between juice and water)
|
|
Were the groups similar at the start of the trial?
|
Yes
|
No (different pregnancy status)
|
Yes
|
Yes
|
|
Aside from the experimental intervention, were the groups treated equally?
|
Yes
|
Yes
|
Yes
|
Can’t tell
|
|
How large was the treatment effect?
|
Significant (p = 0.03)
|
Significant (p ≤ 0.001)
|
Not significant (p = 0.71)
|
Significant (p < 0.05)
|
|
How precise was the estimate of the treatment effect?
|
Precise (95% CI used)
|
Can’t tell (no CI limits)
|
Precise (95% CI used)
|
Can’t tell (no CI limits)
|
|
Can the results be applied in your context? (Or to the local population)
|
Yes
|
Probable
|
Yes
|
Yes
|
|
Were all clinically important outcomes considered?
|
Yes
|
Yes
|
Yes
|
Yes
|
|
Are the benefits worth the harms and costs?
|
Yes
|
Yes
|
N (due to stomach disturbances)
|
No (due to stomach disturbances)
|
