From: Risk factors and outcome of patients with eclampsia at a tertiary hospital in Egypt
Risk factor | Deliveries | Eclampsia | Adjusted Odds ratio (95% CI) | P value |
---|---|---|---|---|
Age: | ||||
 < 20 years | 3732 (17.2%) | 106 (42.4%) | 2.05(1.95-2.28) | <0.001 |
 20-29 years | 12421 (57.3%) | 89 (35.6%) | Reference |  |
 30-34 years | 4107 (18.9%) | 38 (15.2%) | 1.29(1.18-1.39) | 0.185 |
 >35 years | 1430 (6.6%) | 17 (6.8%) | 1.67(1.59-1.71) | 0.05 |
Parity: | ||||
 Nullipara | 7965 (36.7%) | 193 (77.2%) | 3.59(3.03-4.01) | <0.001 |
 Multipara | 13725 (63.3%) | 57 (22.8%) | Reference |  |
BMI | ||||
 <20 | 1483 (6.8%) | 27 (10.8%) | 0.84(0.73-0.95) | 0.59 |
 20 to <25 | 5013 (23.2%) | 52 (20.8%) | Reference |  |
 25 to <30 | 7531 (34.7%) | 41 (16.4%) | 0.52(0.45-0.63) | 0.002 |
 30 to <35 | 6423 (29.6%) | 73 (29.2%) | 1.26(1.15-1.38) | 0.187 |
 ≥35 | 1240 (5.7%) | 57 (22.8%) | 4.59(4.14-4.93) | <0.001 |
Duration of marriage before pregnancy (primigavida) | ||||
 <6 months | 2547 (32%) | 127 (65.8%) | 3.05(2.73-3.59) | <0.001 |
 6-12 months | 4221 (53%) | 54 (28%) | Reference |  |
 >12 months | 1197 (15%) | 12 (6.2% | 0.75(0.62-0.87) | 0.442 |
 Change of partner(second marriage) (multipara) | 221 (1.6%) | 11 (19.3%) | 7.63(6.82-8.96) | <0.001 |
Interval between pregnancies(multipara) | ||||
 <5 years | 5913 (74.2%) | 14 (24.6%) | Reference |  |
 5-10 years | 1340 (16.8%) | 18 (31.6%) | 2.74(2.25-3.36) | <0.001 |
 >10 years | 712 (8.9%) | 25 (43.9%) | 7.33(6.63-8.34) | <0.001 |
Level of education | ||||
 -None | 2378 (11%) | 165 (66%) | 8.24(7.15-9.53) | <0.001 |
 -Primary | 7423 (34.2%) | 62 (24.8%) | 2.42(2.28-2.54) | <0.001 |
 -Secondary | 8537 (39.4%) | 21 (8.4%) | Reference |  |
 -Tertiary | 3352 (15.4%) | 2 (0.8%) | 0.24(0.16-.33) | 0.055 |
Family history of preeclampsia | ||||
 Mother | 173 (0.8%) | 17 (6.8%) | 3.07(2.92-3.18) | <0.001 |
 sister | 194 (0.9%) | 19 (7.6%) | 3.11(2.99-3.22) | <0.001 |
Pre-existing medical problems: | ||||
 -Pre-existing hypertension | 198 (0.9%) | 54 (21.6%) | 8.12(7.09-9.15) | <0.001 |
 -Pre-existing diabetes mellitus | 194 (0.9%) | 39 (15.6%) | 5.63(4.59-6.65) | <0.001 |
 -Pre-existing renal disease. | 47 (0.2%) | 7 (2.8%) | 2.59(1.92-3.15) | <0.001 |
 -Cardiac disease. | 325 (1.5%) | 4 (1.4%) | 1.08(0.98-1.18) | 0.876 |
 -Anaemia | 1865 (8.6%) | 79 (31.6%) | 2.53(2.01-2.92) | <0.001 |
 - Known thrombophilia | 75 (0.4%) | 11 (4.4%) | 2.54(2.09-3.04) | <0.001 |
 Preeclampsia or PIH in previous pregnancy (multipara) | 887 (11.1%) | 34 (59.6%) | 2.69(2.26-3.04) | <0.001 |
 Multiple pregnancy | 453(2.1%) | 10(4%) | 1.15(1.03-1.25) | 0.041 |
Antenatal care visits: | ||||
 0 | 1041 (4.8%) | 75 (30%) | 4.38(3.43-5.39) | <0.001 |
 1-3 visits | 13623(62.8%) | 161 (64.4%) | 1.29(1.18-1.39) | 0.534 |
 4-8 visits | 5769 (26.6%) | 13 (5.2%) | Reference |  |
 >8 visits | 1257 (5.8%) | 1 (0.4%) | 0.35(0.27-0.43) | 0.015 |