Table 3 Key features of Maternal, Charlson and Elixhauser comorbidity indices
From: Measurement properties of comorbidity indices in maternal health research: a systematic review
Maternal Comorbidity Index | Charlson Comorbidity Index | Elixhauser Comorbidity Index | |
|---|---|---|---|
Development | |||
Item generation | Based on clinical relevance and literature, but no consensus method applied | No input from previous index, and no consensus method applied | Based on review of published studies, but no consensus method applied |
Item reduction | Odds ratio and p-value from statistical model applied | Adjusted relative risk from statistical model applied, but no clinical relevance for pregnant population | A series of univariable and multivariable regression models |
Item weighting | Weights of coefficients from statistical model used | Weights of coefficients from statistical model used | No weighting |
Sensibility | |||
Purpose | Predict end-organ injury or death during the delivery hospitalization to 30 days | Predict 1-year mortality | In-hospital mortality |
Population | Women who delivered in hospital | General medical patients | Adult, non-maternal inpatients |
Setting | Hospitals in U.S. | Medical ward in a hospital | Hospitals in California |
Face validity | Exists | Exists | Exists |
Content validity | Reasonable | Challenging | Reasonable |
Feasibility | No study | Marked training required | No study |
Reliability | Not studied | Excellent in general No maternal studies | Not studied |
Criterion validity | |||
Concurrent validity | Not studied | No maternal studies | No maternal studies |