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Table 3 Hyperemesis gravidarum severity groups and neonatal outcome

From: Hyperemesis gravidarum and placental dysfunction disorders

  Values Crude model Adjusted modela
Coefficients (95% CI)b p Coefficients (95% CI)b p
Birthweight (g)c,d
 No HG 3100 (476.6) Reference   Reference  
 Mild HG 3116 (464.4) 16.36 (-44.82; 77.54) 0.60 -4.17 (-68.36; 60.02) 0.90
 Severe HG 3046 (485.7) -53.86 (-211.15; 103.43) 0.50 -171.72 (-333.26; -10.18) 0.04
SGAc
 No HG 212 (16.6) Reference   Reference  
 Mild HG 54 (19.8) 1.24 (0.89; 1.73) 0.20 1.29 (0.87; 1.91) 0.20
 Severe HG 6 (17.6) 1.08 (0.44; 2.64) 0.87 1.74 (0.68; 4.44) 0.25
LBWc
 No HG 101 (7.4) Reference   Reference  
 Mild HG 21 (7.5) 1.03 (0.63; 1.67) 0.92 1.36 (0.74; 2.51) 0.32
 Severe HG 2 (5.6) 0.74 (0.18; 3.13) 0.68 1.44 (0.33; 6.33) 0.63
Gestational age at delivery (in days)e
 No HG 274 (17) Reference   Reference  
 Mild HG 275 (13) 0.27 (-2.22; 2.75) 0.83 -0.03 (-2.60; 2.54) 0.98
 Severe HG 276 (19) 0.48 (-5.99; 6.96) 0.88 -2.20 (-8.81; 4.42) 0.52
Apgar scorec,e
 No HG 9 (0) Reference   Reference  
 Mild HG 9 (0) -0.06 (-0.17; 0.04) 0.24 -0.08 (-0.19; 0.03) 0.15
 Severe HG 9 (0) -0.06 (-0.35; 0.23) 0.67 -0.09 (-0.39; 0.21) 0.56
  1. Abbreviations: CI confidence interval, HG hyperemesis gravidarum, g grams, LBW low birthweight, SGA small for gestational age
  2. aAdjusted model: adjusted for socio-economic status (as reflected by income), smoking status, gravidity, maternal age and pre-pregnancy BMI
  3. bResults are expressed as linear regression coefficients (95% CI) in continuous outcomes or OR (95% CI) from logistic regression in case of dichotomous outcomes
  4. cMultiple pregnancies, stillbirths and miscarriages were excluded from the analyses
  5. dValues are reported as mean and standard deviation (SD)
  6. eValues are reported as median and inter-quartile range (IQR)