Table 4 Background characteristics and pregnancy outcomes in relation to prenatal screening or diagnostic procedures in the Swedish Pregnancy Register 2011 to 2013 (N = 284,789)
From: Prenatal diagnosis in Sweden 2011 to 2013—a register-based study
Variable | CUBa | CVSb | ACc | All othersd | Test of differencee | ||||
|---|---|---|---|---|---|---|---|---|---|
n = 92,207 | n = 2983 | n = 7318 | n = 186,092 | ||||||
n | % | n | % | n | % | n | % | ||
Maternal agef, primiparous women (years) | |||||||||
Mean (SD)g | 31.34 (5.17) | 33.79 (5.74) | 33.65 (6.11) | 27.09 (4.58) | <0.001 | ||||
Min-max | 15.09–56.30 | 17.29–49.03 | 16.74–49.83 | 13–54 | |||||
Median (IQR)h | 31.34 (7.32) | 34.41 (8.38) | 34.92 (9.15) | 27.51 (6.41) | |||||
Maternal agef, multiparous women (years) | |||||||||
Mean (SD)g | 34.45 (4.45) | 36.87 (4.65) | 37.13 (4.66) | 30.29 (4.52) | <0.001 | ||||
Min-max | 16.41–55.34 | 19.10–51.76 | 16.41–48.68 | 15–57 | |||||
Median (IQR)h | 34.97 (5.72) | 37.58 (5.66) | 37.82 (5.45) | 30.87 (6.07) | |||||
Maternal agef in age-groups (years) | |||||||||
< 20 | 388 | 0.4 | 8 | 0.3 | 23 | 0.3 | 3566 | 1.9 | |
20–24 | 5863 | 6.4 | 99 | 3.3 | 313 | 4.3 | 32,702 | 17.6 | |
25–29 | 17,617 | 19.1 | 300 | 10.1 | 733 | 10.0 | 65,926 | 35.4 | |
30–34 | 31,792 | 34.5 | 649 | 21.8 | 1314 | 18.0 | 62,944 | 33.8 | |
35–39 | 30,179 | 32.7 | 1262 | 42.3 | 3148 | 43.0 | 17,676 | 9.5 | |
40–44 | 6093 | 6.6 | 628 | 21.1 | 1675 | 22.9 | 2991 | 1.6 | |
> 44 | 270 | 0.3 | 36 | 1.2 | 109 | 1.5 | 211 | 0.1 | |
Body mass index (kg/m2) | |||||||||
Mean (SD)g | 24.40 (4.34) | 24.10 (4.10) | 24.94 (4.52) | 24.99 (4.80) | <0.001 | ||||
Min-max | 13.82–56.65 | 15.24–51.31 | 15.24–50.69 | 13.03–71.63 | |||||
Median (IQR)h | 23.45 (5.0) | 23.18 (5.0) | 24.01 (5.0) | 23.95 (6.0) | |||||
< 18.5 | 1965 | 2.2 | 52 | 1.8 | 121 | 1.7 | 4766 | 2.6 | |
18.5–24.99 | 56,723 | 63.2 | 1918 | 66.3 | 4140 | 58.2 | 103,359 | 57.2 | |
25–29.99 | 21,639 | 24.1 | 663 | 22.9 | 1926 | 27.1 | 47,160 | 26.1 | |
30–34.99 | 6863 | 7.6 | 195 | 6.7 | 652 | 9.2 | 17,741 | 9.8 | |
35.39.99 | 1992 | 2.2 | 48 | 1.7 | 203 | 2.9 | 5744 | 3.2 | |
≥ 40 | 629 | 0.7 | 18 | 0.6 | 68 | 1.0 | 2071 | 1.1 | |
Educational level | |||||||||
Elementary school | 3242 | 4.1 | 69 | 2.7 | 334 | 5.3 | 17,353 | 11.2 | <0.001 |
High school | 24,324 | 31.1 | 608 | 23.7 | 2078 | 33.1 | 69,523 | 44.8 | |
University | 50,763 | 64.8 | 1887 | 73.6 | 3869 | 61.6 | 68,302 | 44.0 | |
Main occupation | |||||||||
Employed | 72,519 | 80.3 | 2439 | 83.7 | 5582 | 77.8 | 118,371 | 65.0 | <0.001 |
Student | 6467 | 7.2 | 146 | 5.0 | 524 | 7.3 | 24,121 | 13.3 | |
Parental leave | 5059 | 5.6 | 149 | 5.1 | 459 | 6.4 | 15,002 | 8.2 | |
Unemployed | 3320 | 3.7 | 78 | 2.7 | 294 | 4.1 | 11,601 | 6.4 | |
Sick leave | 1306 | 1.4 | 36 | 1.2 | 119 | 1.7 | 3009 | 1.7 | |
Other | 1610 | 1.8 | 66 | 2.3 | 194 | 2.7 | 9897 | 5.4 | |
Country of birth | |||||||||
Sweden | 76,276 | 84.5 | 2482 | 85.4 | 5876 | 81.8 | 139,881 | 76.7 | <0.001 |
Other Nordic countriesi | 904 | 1.0 | 31 | 1.1 | 74 | 1.0 | 1406 | 0.8 | |
Europej | 3971 | 4.4 | 102 | 3.5 | 332 | 4.6 | 8617 | 4.7 | |
Africa | 1243 | 1.4 | 37 | 1.3 | 127 | 1.8 | 9438 | 5.2 | |
Asia | 6132 | 6.8 | 196 | 6.7 | 590 | 8.2 | 18,955 | 10.4 | |
Other | 1727 | 1.9 | 57 | 2.0 | 180 | 2.5 | 4007 | 2.2 | |
Smoking 3 months prior to pregnancy | 9583 | 10.5 | 229 | 7.7 | 751 | 10.3 | 28,659 | 15.6 | <0.001 |
Smoking at first ANCk visit | 3445 | 3.8 | 76 | 2.6 | 347 | 4.8 | 12,144 | 6.6 | <0.001 |
Smoking at 32 weeks of gestation | 2527 | 2.8 | 48 | 1.6 | 289 | 4.0 | 9238 | 5.0 | <0.001 |
Use of snuff 3 month prior to pregnancy | 2493 | 2.7 | 64 | 2.2 | 213 | 2.9 | 7268 | 3.9 | <0.001 |
Use of snuff at first ANC visit | 646 | 0.7 | 22 | 0.7 | 85 | 1.2 | 2134 | 1.2 | <0.001 |
Use of snuff at 32 weeks of gestation | 385 | 0.4 | 13 | 0.4 | 41 | 0.6 | 1303 | 0.7 | <0.001 |
Alcohol screening (AUDIT)l | 81,686 | 90.3 | 2568 | 88.4 | 6313 | 86.3 | 158,335 | 87.0 | <0.001 |
AUDIT-scorem | |||||||||
Mean (SD) | 2.34 (1.96 | 2.26 (1.74) | 2.12 (1.90 | 2.11 (2.32) | |||||
Min-max | 0–38 | 0–18 | 0–29 | 0–40 | |||||
Median (IQR)h | 2.00 (2) | 2.00 (2) | 2.00 (2) | 2.00 (3) | |||||
≤ 5p | 76,786 | 94.5 | 2462 | 96.3 | 6012 | 95.7 | 82,067 | 94.6 | <0.001 |
≥ 6p | 4485 | 5.5 | 95 | 3.7 | 270 | 4.3 | 4703 | 5.4 | |
Self-rated health prior to pregnancy | |||||||||
Very good | 25,990 | 33.0 | 834 | 32.5 | 1887 | 30.5 | 44,643 | 28.3 | <0.001 |
Good | 44,563 | 56.6 | 1433 | 55.9 | 3489 | 56.5 | 93,611 | 59.4 | |
Neither good nor poor | 5877 | 7.5 | 217 | 8.5 | 583 | 9.4 | 14,047 | 8.9 | |
Poor | 1817 | 2.3 | 64 | 2.5 | 187 | 3.0 | 4334 | 2.7 | |
Very poor | 440 | 0.6 | 15 | 0.6 | 34 | 0.6 | 1056 | 0.7 | |
Counselling due to fear of childbirth | 8900 | 9.7 | 324 | 10.9 | 745 | 10.2 | 12,023 | 6.5 | <0.001 |
Treatment of psychiatric disorder | 6002 | 6.5 | 185 | 6.3 | 533 | 7.3 | 11,275 | 6.1 | <0.001 |
Gestational age (days) | |||||||||
Mean (SD)g | 278.0 (13.7) | 276.6 (15.0) | 276.5 (15.4) | 278.0 (13.8) | 0.326 | ||||
Min-max | 154–301 | 158–300 | 157–301 | 154–301 | |||||
Median (IQR)h | 280.0 (13.0) | 279.0 (13.0) | 279 (15.0) | 280 (13.00) | |||||
Mode of delivery | |||||||||
Vaginal | 6885 | 73.9 | 2079 | 70.2 | 5133 | 70.3 | 145,486 | 78.5 | <0.001 |
Instrumental | 6376 | 6.9 | 163 | 5.5 | 392 | 5.4 | 12,468 | 6.7 | |
Caesarean section | 17,574 | 19.1 | 721 | 24.3 | 1772 | 24.3 | 27,405 | 14.8 | |
Caesarean section (CS) n | |||||||||
Elective CSn | 8650 | 49.3 | 297 | 58.7 | 916 | 51.7 | 10,700 | 39.1 | <0.001 |
Emergency CSn | 8893 | 50.7 | 422 | 41.3 | 855 | 48.3 | 16,639 | 60.9 | |
Birth weight (grams)o | |||||||||
Mean (SD)g | 3549 (552) | 3531 (585) | 3510 (620) | 3539 (557) | 0.001 | ||||
Min-max | 310–6270 | 400–5710 | 370–5776 | 300–6640 | |||||
Median (IQR)h | 3560 (665) | 3555 (686) | 3548 (706) | 3545 (680) | |||||