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Table 2 Perinatal Outcomes of the RPGEH Prenatal Cohort Participants Compared to Non-Participants in Kaiser Permanente Northern California

From: The Kaiser Permanente Northern California research program on genes, environment, and health (RPGEH) pregnancy cohort: study design, methodology and baseline characteristics

 

Overall Denominator (n = 80,086)

Participants (n = 14,757)

Non-Participants (n = 65,329)

Perinatal Outcome

 

N (%)

 

Preeclampsia

 None

71,368 (89.1)

13,017 (88.2)

58,315 (89.3)

 Pre-existing hypertension

2,441 (3.1)

524 (3.4)

1,917 (2.9)

 Gestational hypertension

3,079 (3.8)

604 (4.1)

2,475 (3.8)

 Preeclampsia/Eclampsia

3,198 (4.0)

612 (4.1)

2,586 (4.0)

Glucose Tolerance Status

 Normal Screening

56,461 (70.5)

10,861 (73.6)

45,599 (69.8)

 Abnormal Screening

12,013 (15.0)

2,125 (14.4)

9,930 (15.2)

 Gestational Diabetes

5,366 (6.7)

959 (6.5)

4,508 (6.9)

 Preexisting T2DM

961 (1.2)

162 (1.1)

784 (1.2)

 Not Screened

4,805 (6.4)

649 (4.4)

4,508 (6.9)

Gestational Age

  < 37 weeks

6,063 (7.6)

1,095 (7.4)

4,968 (7.6)

  ≥ 37 weeks

74,005 (92.4)

13,662 (92.6)

60,343 (92.4)

 Unknown

18 (<0.1)

0 (0)

18 (<0.1)

Gestational Age

 Extreme Preterm (<28 weeks)

324 (0.4)

57 (0.4)

267 (0.4)

 Severe Preterm (28–31 week)

526 (0.7)

91 (0.6)

435 (0.7)

 Moderate Preterm (32–33 weeks)

698 (0.9)

116 (0.8)

582 (0.9)

 Late Preterm (34–36 weeks)

4,515 (5.6)

831 (5.6)

3,684 (5.6)

  ≥ 37 weeks

74,005 (92.4)

13,662 (92.6)

60,343 (92.4)

 Unknown

18 (<0.1)

0 (0)

18 (<0.1)

Gestational weight gain in relation to the IOM weight gain guidelines

 Below

10,456 (13.1)

1,847 (12.5)

8,609 (13.2)

 Met

17,196 (21.5)

3,115 (21.1)

14,081 (21.6)

 Exceeded

48,689 (60.8)

9,416 (63.8)

39,273 (60.1)

 Unknown

3,745 (4.7)

379 (2.6)

3,366 (5.2)

 Infant birth weight (grams)a

3,361 ± 556

3,400 ± 565

3,350 ± 553

 AGA

63,843 (81.4)

11,771 (81.3)

52,072 (81.4)

 SGA

7,436 (9.5)

1,339 (9.3)

6,097 (9.5)

 LGA

6,992 (8.9)

1,342 (9.3)

5,650 (8.8)

 Unknown

135 (0.2)

17 (0.1)

118 (0.2)

Infant birth weight (grams)

 Very low birth weight (<1,500)

605 (0.8)

106 (0.7)

499 (0.8)

 Low birth weight (1,500–2,500)

3,158 (4.0)

555 (3.8)

2,603 (4.1)

 Normal birth weight (2,501–3,999)

65,975 (84.2)

12,042 (83.2)

53,933 (84.4)

 Macrosomia (4,000+)

8,582 (10.9)

1,757 (12.2)

6,825 (10.7)

 Unknown

86 (0.1)

9 (0.1)

77 (0.1)

NICU Stay

 Non-NICU

71,563 (89.4)

13,092 (88.7)

58,471 (89.5)

 NICU

8,393 (10.5)

1,647 (11.2)

6,746 (10.3)

 Delivery room death

112 (0.1)

17 (0.1)

95 (0.2)

 Unknown

18 (<0.1)

1 (<0.1)

17 (<0.1)

  1. aLGA is large-for-gestational age, adjusted for race/ethnicity
  2. SGA is small-for-gestational age, adjusted for race/ethnicity
  3. AGA is appropriate for-gestational age, adjusted for race/ethnicity