Skip to main content

Table 1 Patient characteristics and pregnancy outcome parameters

From: The usefulness of CYFRA 21–1 to diagnose and predict preeclampsia: a nested case-control study

  Total Control (1) PE_long (2) PE_state (3) p global p 1 vs 2 p 1 vs 3
n 110 50 10 50    
Maternal Age 31.28 ± 6.4 29.9 ± 6 32.1 ± 6.4 32.5 ± 6.63 0,116a 0,336b 0,042b
Maternal BMI 24.99 ± 4.8 23.44 ± 3.9 27.2 ± 3.53 26.09 ± 5.38 0,006a 0,009b 0,006b
Smoking in pregnancy      0,057c 0,715c 0,040c
 NO 89 (81 %) 36 (72 %) 8 (80 %) 45 (90 %)    
 YES 21 (19 %) 14 (28 %) 2 (20 %) 5 (10 %)    
Parity      0,002c 0,406c <0.001c
 0 50 (48 %) 19 (38 %) 4 (40 %) 27 (61 %)    
 1/2 46 (44 %) 30 (60 %) 5 (50 %) 11 (25 %)    
  > 2 8 (8 %) 1 (2 %) 1 (10 %) 6 (14 %)    
GA at Delivery (weeks) 35.75 ± 4.84 39.59 ± 1.27 34.97 ± 4.42 32.05 ± 4.23 <0.001a 0,009b <0.001b
Mode of Delivery      <0.001c <0.001c <0.001c
 Caesarean section 70 (64 %) 17 (34 %) 10 (100 %) 43 (86 %)    
 Vaginal delivery 40 (36 %) 33 (66 %) 0 (0 %) 7 (14 %)    
Neonatal birth weight (grams) 2471.23 ± 1132.82 3403.8 ± 398.16 1988.2 ± 784.89 1635.26 ± 966.85 <0.001a <0.001b <0.001b
Transfer of newborn to NICU     <0.001c <0.001c <0.001c
 NO 72 (65 %) 50 (100 %) 4 (40 %) 18 (36 %)    
 YES 38 (35 %) 0 (0 %) 6 (60 %) 32 (64 %)    
Gender of newborn      0,324c 0,299c 0,840c
 female 59 (54 %) 27 (54 %) 3 (30 %) 29 (58 %)    
 male 51 (46 %) 23 (46 %) 7 (70 %) 21 (42 %)    
  1. Categorical data are presented as the frequency and percentage (rounded). Continuous variables are expressed as the mean ± SD
  2. GA gestational age, BMI pre-prenancy body mass index, NICU neonatal intensive care unit
  3. aANOVA; bStudent’s t-test; cFisher’s exact test