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Table 2 Results of univariate logistic regression analysis on influencing factors of NSCL/P

From: A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors

Screened factors Controls
(n = 226)
Cases
(n = 113)
b c P ORa 95 % CIb (OR)
Education level, n (%)     0.031*    
 College and above 56 (24.8) 21 (18.6)    1   
 Middle school 160 (70.8) 79 (69.9) 0.500 0.206 1.650 0.760 3.582
 Primary school and below 10 (4.4) 13 (11.5) 1.542 0.009* 4.673 1.476 14.795
Family income (Yuan/year/person), n (%)     0.003*    
 > 15,000 22 (9.7) 6 (5.3)    1   
 10,001–15,000 10 (4.4) 1 (0.9) −1.003 0.381 0.367 0.039 3.462
 5001–10,000 107 (47.3) 39 (34.5) 0.290 0.056 1.336 0.504 3.541
 ≤ 5000 87 (38.5) 67 (59.3) 1.038 0.034* 2.824 1.084 7.355
Premarital medical examination, n (%) 56 (24.8) 13 (11.5) −0.930 0.005* 0.395 0.206 0.757
Upper respiratory tract infection, n (%) 75 (33.2) 55 (48.7) 0.647 0.006* 1.909 1.204 3.028
Complications of pregnancy, n (%) 6 (2.7) 9 (8.0) 1.155 0.033* 3.173 1.100 9.149
Contraceptive intake before pregnancy, n (%) 2 (0.9) 6 (5.3) 1.837 0.026* 6.280 1.247 31.634
Maternal occupational hazards exposure, n (%) 5 (2.2) 16 (14.2) 1.987 0.000* 7.291 2.597 20.466
Housing renovation, n (%) 11 (4.9) 21 (18.6) 1.495 0.000* 4.461 2.067 9.629
Fish/shrimp/meat/eggs intake, n (%)     0.033*    
 ≤ 2 times/week 16 (7.1) 15 (13.3)    1   
 3~5 times/week 79 (35.0) 48 (42.5) −0.434 0.282 0.648 0.294 1.429
 > 5 times/week 131 (58.0) 50 (44.2) −0.899 0.023* 0.407 0.187 0.885
Milk/soymilk intake, n (%)     0.000*    
 ≤ 2 times/week 26 (11.5) 35 (31.0)    1   
 3~5 times/week 82 (36.3) 36 (31.9) −1.120 0.001* 0.326 0.172 0.619
 > 5 times/week 118 (52.2) 42 (37.2) −1.330 0.000* 0.143 0.143 0.490
Paternal occupational hazards exposure, n (%) 3 (1.3) 14 (12.4) 2.352 0.000* 10.512 2.954 37.402
Paternal strong tea drinking, n (%) 20 (8.8) 20 (17.7) 0.795 0.019* 2.215 1.138 4.313
Family history of NSCL/P, n (%) 2 (0.9) 13 (11.5) 6.678 0.000* 14.560 3.225 65.728
  1. aOR denotes odds ratio; bCI denotes confidence interval; cb denotes partial regression coefficient; *P < 0.05