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Table 2 Results of univariate logistic regression analysis on influencing factors of NSCL/P

From: A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors

Screened factors

Controls

(n = 226)

Cases

(n = 113)

b c

P

ORa

95 % CIb (OR)

Education level, n (%)

   

0.031*

   

 College and above

56 (24.8)

21 (18.6)

  

1

  

 Middle school

160 (70.8)

79 (69.9)

0.500

0.206

1.650

0.760

3.582

 Primary school and below

10 (4.4)

13 (11.5)

1.542

0.009*

4.673

1.476

14.795

Family income (Yuan/year/person), n (%)

   

0.003*

   

 > 15,000

22 (9.7)

6 (5.3)

  

1

  

 10,001–15,000

10 (4.4)

1 (0.9)

−1.003

0.381

0.367

0.039

3.462

 5001–10,000

107 (47.3)

39 (34.5)

0.290

0.056

1.336

0.504

3.541

 ≤ 5000

87 (38.5)

67 (59.3)

1.038

0.034*

2.824

1.084

7.355

Premarital medical examination, n (%)

56 (24.8)

13 (11.5)

−0.930

0.005*

0.395

0.206

0.757

Upper respiratory tract infection, n (%)

75 (33.2)

55 (48.7)

0.647

0.006*

1.909

1.204

3.028

Complications of pregnancy, n (%)

6 (2.7)

9 (8.0)

1.155

0.033*

3.173

1.100

9.149

Contraceptive intake before pregnancy, n (%)

2 (0.9)

6 (5.3)

1.837

0.026*

6.280

1.247

31.634

Maternal occupational hazards exposure, n (%)

5 (2.2)

16 (14.2)

1.987

0.000*

7.291

2.597

20.466

Housing renovation, n (%)

11 (4.9)

21 (18.6)

1.495

0.000*

4.461

2.067

9.629

Fish/shrimp/meat/eggs intake, n (%)

   

0.033*

   

 ≤ 2 times/week

16 (7.1)

15 (13.3)

  

1

  

 3~5 times/week

79 (35.0)

48 (42.5)

−0.434

0.282

0.648

0.294

1.429

 > 5 times/week

131 (58.0)

50 (44.2)

−0.899

0.023*

0.407

0.187

0.885

Milk/soymilk intake, n (%)

   

0.000*

   

 ≤ 2 times/week

26 (11.5)

35 (31.0)

  

1

  

 3~5 times/week

82 (36.3)

36 (31.9)

−1.120

0.001*

0.326

0.172

0.619

 > 5 times/week

118 (52.2)

42 (37.2)

−1.330

0.000*

0.143

0.143

0.490

Paternal occupational hazards exposure, n (%)

3 (1.3)

14 (12.4)

2.352

0.000*

10.512

2.954

37.402

Paternal strong tea drinking, n (%)

20 (8.8)

20 (17.7)

0.795

0.019*

2.215

1.138

4.313

Family history of NSCL/P, n (%)

2 (0.9)

13 (11.5)

6.678

0.000*

14.560

3.225

65.728

  1. aOR denotes odds ratio; bCI denotes confidence interval; cb denotes partial regression coefficient; *P < 0.05
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