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Table 8 Rates respiratory distress syndrome (RDS) at 32–36 weeks and 37–38 weeks per 1000 live births among infants with other neonatal morbidity, and unadjusted odds ratios and 95 % confidence intervals (CI) expressing the association between neonatal comorbidity and RDS at 32–36 weeks and 37–38 weeks, United States, 2005–2006

From: Heterogeneity of respiratory distress syndrome: risk factors and morbidity associated with early and late gestation disease

 

RDS 32–36 weeks

RDS 37–38 weeks

No.

Rate per 1000

Odds ratio [95 % CI]

No.

Rate per 1000

Odds ratio [95 % CI]

Apgar at 5 minutes

<4

165

85.2

3.13 [2.67, 3.68]

50

34.5

11.4 [8.6, 15.1]

4–6

733

99.9

3.73 [3.45, 4.04]

309

45.1

15.0 [13.3, 16.9]

≥7

11,009

28.9

Reference

3917

3.1

Reference

Small for gestational age

2202

32.7

1.09 [1.04, 1.14]

645

4.8

1.48 [1.36, 1.61]

Neonatal seizures

27

102.3

3.63 [2.44, 5.40]

12

20.1

6.04 [3.41, 10.70]

Ventilation ≥ 30 min

3428

236.1

13.4 [12.8, 14.0]

858

144.4

61.5 [56.8, 66.6]

Ventilation <30 min

766

64.9

2.29 [2.12, 2.47]

294

16.3

5.14 [4.56, 5.79]

Birth asphyxia

4244

153.1

8.37 [8.05, 8.71]

1175

46.3

19.2 [18.0, 20.6]

Meconium aspiration syndrome

38

140.7

5.22 [3.70, 7.36]

66

72.8

23.3 [18.1, 30.0]

All live births

11,942

30.5

-

4292

3.4

-

  1. Birth asphyxia was defined as Apgar at 5 minute <4, presence of neonatal seizures, or any assisted ventilation. Births with missing Apgar values excluded from the analysis. Odds ratios were estimated by contrasting outcomes among those with and those without the risk factor e.g., RDS at 37–38 weeks among infants with and without meconium aspiration syndrome