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Table 3 Cardiac screening findings in confirmed CHD fetuses and clinical outcomes

From: Identification of fetal cardiac anatomy and hemodynamics: a novel enhanced screening protocol

Cardiac lesions (n)

Referred for echocardiography (n)

Outcomes (n)

Protocol A

Protocol B

 

Cardiac position

   

 Complete situs inversus (2)

0

2

NNA (2)

 Dextrocardia (1)

1

1

TOP (1)

 Heterotaxy (1)

0

1

NND (1)

 Cardiomediastinal shift (2)

2

2

NNA (2)

Venous connection

   

 TAPVC (1)

0

1

NNA (1)

 LSVC (2)

1

2

NNA (2)

 LSVC without RSVC (1)

0

1

IUFD (1)

 Interrupted IVC (1)

0

1

NNA (1)

Septal defects

   

 Large VSD (3)

3

3

NND (1); NNA (2)

 Small VSD (2)

0

1

NNA (2)

 CAVSD (2)

2

2

TOP (1); NNA (1)

 PAVSD (1)

1

1

NNA (1)

Left heart anomalies

   

 HLHS (4)

4

4

TOP (4)

 COA (1)

0

0

NND (1)

 IAA and VSD (1)

1

1

TOP (1)

 Right aortic arch (2)

0

2

NNA (2)

 Aortic valve atresia (1)

1

1

IUFD (1)

Right heart anomalies

   

 HRHS (1)

1

1

TOP (1)

 Ebstein’s anomaly (2)

2

2

IUFD (1); NNA (1)

 Tricuspid dysplasia (1)

0

1

NND (1)

 Tricuspid stenosis (1)

0

1

NNA (1)

 Pulmonary atresia (2)

0

2

TOP (1); NND (1)

 Pulmonary stenosis (1)

0

1

NNA (1)

 Absent pulmonary valve (1)

1

1

IUFD (1)

Conotruncal anomalies

   

 TOF (2)

2

2

NNA (2)

 TGA (3)

1

3

TOP (1); NND (2)

 ccTGA (1)

0

1

NNA (1)

 Taussig-Bing (1)

1

1

TOP (1)

 DORV (3)

3

3

TOP (1); NNA (2)

 CTA (2)

2

2

TOP (1); NNA (1)

Complex CHDs (3)

3

3

TOP (3)

 Total (52)

32

50

NNA(25); NND (7); IUFD (4); TOP (16)

  1. CAVSD complete atrioventricular septal defect, ccTGA congenitally corrected transposition of the great arteries, COA coarctation of aorta, CTA conotruncal anomalies, DORV double outlet right ventricle, HLHS hypoplastic left heart syndrome, HRHS hypoplastic right heart syndrome, IAA interrupted aortic arch, IUFD intrauterine fetal death, IVC inferior vena cava, LSVC left superior vena cava, NNA, neonatal alive, NND neonatal death, PAVSD partial atrioventricular septal defect, RSVC right superior vena cava, TAPVC total anomalous pulmonary venous connection, TGA transposition of the great arteries, TOF tetrology of Fallot, TOP termination of pregnancy, VSD ventricular septal defect