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Fig. 3 | BMC Pregnancy and Childbirth

Fig. 3

From: Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta

Fig. 3

Effect of statins on soluble endoglin secretion from primary human tissues. a Simvastatin (0, 1, 2, 5 μM), rosuvastatin (0, 1, 2, 5, μM) and pravastatin (0, 2, 5, 200 μM) all caused an increase in soluble endoglin secretion from primary HUVECs. b Statin treatment did not alter sEng secretion from preterm preeclamptic explants. Data represents n = 3–4 separate experiments and is expressed as mean ± SEM. Dark blue bars = control, light blue bars = statin treatments. a = p < 0.05, b = p < 0.01, d = p < 0.0001

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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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