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Table 4 Review of the literature and pooled analysis of studies with reported histo-pathological outcome

From: Natural history of cervical intraepithelial neoplasia in pregnancy: postpartum histo-pathologic outcome and review of the literature

Author, Date N Population Analysis Regression Persistence Progression
Lurain [19] 53 Pregnant women with CIN I–III Retrospective 77.4 % 22.6 % 0 %
Yost [7] 153 Pregnant women with CIN II–III Retrospective 69.3 % 26.8 % 3.9 %
Palle [16] 142 Pregnant women with CIN I–III Retrospective 25 % 47 % 28 %
Vlahos [8] 78 Pregnant women with CIN II–III Retrospective 61.6 % 38.4 % 0 %
Paraskevaides [9] 64 Pregnant women with CIN II–III Retrospective 37.5 % 59.4 % 3.1 %
Serati [15] 36 Pregnant women with CIN II–III Prospective 47.3 % 52.7 % 0 %
Coppolillo [11] 30 Pregnant women with CIN II–III Retrospective 16.7 % 70.0 % 13.3 %
Kärrberg [17] 163 Pregnant women with CIN I–III Prospective 33.1 % 54.6 % 12.3 %
This study 51 Pregnant women with CIN I–III Retrospective 56.9 % 39.2 % 3.9 %
Pooled analysis 770 Pregnant women with CIN I–III Pooled 46.8 % 43.6 % 9.6 %