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Table 5 Optimal cut-off points of maternal third-trimester lipids for predicting pregnancy complications and perinatal outcomes

From: Associations between maternal lipid profile and pregnancy complications and perinatal outcomes: a population-based study from China

Outcomes

AUC (95 % CI)

Sensitivity (%)

Specificity (%)

Youden index

Cut-off point (mmol/L)

TG

     

 GDM

0.633 (0.566-0.701)

47.9

74.2

0.221

3.871

 Preeclampsia

0.736 (0.595-0.876)

85.7

64.8

0.505

3.528

 ICP

0.607 (0.528-0.685)

66.1

55.9

0.220

3.177

 LGA

0.571 (0.529-0.613)

44.7

67.4

0.121

3.534

 SGA

0.658 (0.540-0.775)

63.6

68.9

0.325

2.530

HDL-C

     

 GDM

0.617 (0.548-0.686)

57.7

61.2

0.189

1.712

 Macrosomia

0.592 (0.527-0.657)

66.7

49.8

0.165

1.817

 SGA

0.606 (0.457-0.756)

40.9

88.7

0.296

2.238

LDL-C

     

 GDM

0.649 (0.582-0.715)

54.9

71.7

0.266

2.415

  1. AUC area under curve, CI confidence interval, GDM gestational diabetes mellitus, ICP intrahepatic cholestasis of pregnancy, SGA/LGA small/large for gestational age, TG triglycerides, HDL-C/LDL-C high-density/low-density lipoprotein-cholesterol