Serum level and polymorphisms of retinol-binding protein-4 and risk for gestational diabetes mellitus: a meta-analysis

Table 2 Detailed characteristics of all eligible studies for the association with RBP4 gene polymorphisms and GDM

Gene polymorphisms	Author	Year	Country	Ethnicity	Case include	No of case	No of control	Genotype^a		P for HWE
Gene polymorphisms	Author	Year	Country	Ethnicity	Case include	No of case	No of control	Case	Control	P for HWE
rs3758539	Hiraoka a^d [11]	2011	America	Utah Caucasian	GDM	88	315	56/31/1	228/77/10	0.27
	Hiraoka b^d [11]	2011	America	Hawai‘i Filipino	GDM	82	286	63/16/3	226/55/5	0.44
	Hiraoka c^d [11]	2011	America	Hawai‘i Pacific Islander	GDM	19	32	18/1/0	23/9/0	0.35
	Ping^e [12]	2012	China	Han	GDM + GIGT^c	723	872	375/75/5	462/143/8	0.41
	Saucedo^d [13]	2014	Mexico	Unclear	GDM	100	100	93/7	91/9	P > 0.05^b
rs12265684	Ping^e [12]	2012	China	Han	GDM + GIGT^c	723	872	382/106/5	483/168/14	0.89
rs3758538	Ping^d [12]	2012	China	Han	GDM + GIGT^c	723	872	414/63/4	562/76/2	0.74
rs10882273	Ping^d [12]	2012	China	Han	GDM + GIGT^c	723	872	363/107/8	451/174/13	0.42
rs116736522	Saucedo^d [13]	2014	Mexico	Unclear	GDM	100	100	97/3	96/4	P > 0.05^b
rs34571439	Saucedo^d [13]	2014	Mexico	Unclear	GDM	100	100	91/9	88/12	P > 0.05^b

^aGenotype for rs3758539, GG/AG/AA (For Saucedo, GG/GA + AA); rs12265684, CC/CG/GG; rs3758538, AA/AC/CC; rs10882273, TT/TC/CC; rs116736522, GG/GC + CC; rs34571439, AA/AC + CC
^bNo sufficient data to calculate the P for HWE. Authors mentioned “all variants are in the Hardy-Weinberg equilibrium” in the article
^c GIGT gestational impaired glucose tolerance
^dNo significant differences was found in allelic frequencies between case and control groups
^eSignificant differences was found in allelic frequencies between case and control groups

ISSN: 1471-2393