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Table 3 Outcomes from the births of all women who gave birth at home (or family/TBA home). Data on haemoglobin is taken from those for whom a follow-up assessment was completed within 5 days of delivery

From: The MamaMiso study of self-administered misoprostol to prevent bleeding after childbirth in rural Uganda: a community-based, placebo-controlled randomised trial

Haemoglobin Measures (women seen within 5 days of delivery)
  Misoprostol (n = 97) Placebo (n = 80) Relative risk or mean difference (95 % CI)
Days from birth to follow-up (mean, (SD)) 3.6 (0.7) 3.5 (0.7) 0.07 (−0.14 : 0.28)
Fall in Hb >20 % (n, %) 9 ( 9.4) 6 ( 7.5) 1.110 (0.717 : 1.719)
Fall in Hb > 2 g/dl (n, %) 13 (13.4) 8 (10.0) 1.150 (0.798 : 1.657)
Postnatal Hb g/dl (mean (SD) [range]) 11.1 (1.8) [5.2:15.3] 11.2 (1.4) [6.1:14.0] −0.11 (−0.59 : 0.37)
Anaemia status* (n,%)
Normal 51 (52.6) 46 (57.5) ---
Mild 36 (37.1) 28 (35.0) 1.070 (0.803 : 1.426)
Moderate 8 ( 8.2) 5 ( 6.2) 1.170 (0.732 : 1.872)
Severe 2 ( 2.1) 1 ( 1.2) 1.268 (0.557 : 2.885)
Fall in Hb g/dl (mean (SD) [range]) 0.06 (1.82) [−5.5:5.2] 0.09 (1.50) [−3.5:4.0] −0.03 (−0.53 : 0.47)
Maternal and Neonatal Outcomes (all home births)
  Misoprostol (n = 150) Placebo (n = 149) Relative risk or mean difference (95 % CI)
Days from birth to follow-up (median (IQR)) 4 (3 – 13) 5 (3 – 25) ---
Maternal complications (n, %)
Health professional consulted 2 ( 1.3) 3 ( 2.0) 0.795 (0.525 : 1.427)
Admitted to a health facility >24 hours** 1 ( 0.7) 1 ( 0.7) 0.997 (0.517 : 1.691)
Surgical procedure since delivery*** 0 1 ( 0.7) ---
Retained placenta 3 ( 2.0) 2 ( 1.3) 1.200 (0.581 : 2.477)
Blood transfusion after delivery 0 0 ---
Use of additional uterotonics (n, %) 3 (2.0) 4 (2.7) 0.745 (0.189 : 2.928)
Self-reported side effects (n, %)
Shivering/chills after birth 75 (51.0) 40 (27.8) 1.594 (1.277 : 1.991)
Fever after birth 40 (27.2) 21 (14.6) 1.410 (1.121 : 1.772)
Diarrhoea within 24 hours 4 ( 2.7) 1 ( 0.7) 1.600 (1.017 : 2.518)
Neonatal Death (n, %) 0 3 ( 2.0) ---
If ‘yes, when did the baby die? (n, %)
Before birth 0 1 (33.3) ---
Within 24 hours of birth 0 0
More than 24 hours after birth 0 2 (66.7)
  1. * Anaemia shown by WHO classification: normal (>11 g/dl), mild (9–10.99 g/dl), moderate (7.8.99 g/dl) and severe (<7 g/dl).
  2. ** Misoprostol: admitted with Hb <6 g/dl; placebo: admitted for drainage of breast abscess
  3. *** Drainage of breast abscess
  4. † Respondents could have more than one response. Data missing for 3 in the misoprostol group and 5 in the placebo group.