Haemoglobin Measures (women seen within 5 days of delivery) | |||
---|---|---|---|
Misoprostol (n = 97) | Placebo (n = 80) | Relative risk or mean difference (95 % CI) | |
Days from birth to follow-up (mean, (SD)) | 3.6 (0.7) | 3.5 (0.7) | 0.07 (−0.14 : 0.28) |
Fall in Hb >20 % (n, %) | 9 ( 9.4) | 6 ( 7.5) | 1.110 (0.717 : 1.719) |
Fall in Hb > 2 g/dl (n, %) | 13 (13.4) | 8 (10.0) | 1.150 (0.798 : 1.657) |
Postnatal Hb g/dl (mean (SD) [range]) | 11.1 (1.8) [5.2:15.3] | 11.2 (1.4) [6.1:14.0] | −0.11 (−0.59 : 0.37) |
Anaemia status* (n,%) | |||
Normal | 51 (52.6) | 46 (57.5) | --- |
Mild | 36 (37.1) | 28 (35.0) | 1.070 (0.803 : 1.426) |
Moderate | 8 ( 8.2) | 5 ( 6.2) | 1.170 (0.732 : 1.872) |
Severe | 2 ( 2.1) | 1 ( 1.2) | 1.268 (0.557 : 2.885) |
Fall in Hb g/dl (mean (SD) [range]) | 0.06 (1.82) [−5.5:5.2] | 0.09 (1.50) [−3.5:4.0] | −0.03 (−0.53 : 0.47) |
Maternal and Neonatal Outcomes (all home births) | |||
Misoprostol (n = 150) | Placebo (n = 149) | Relative risk or mean difference (95 % CI) | |
Days from birth to follow-up (median (IQR)) | 4 (3 – 13) | 5 (3 – 25) | --- |
Maternal complications (n, %)† | |||
Health professional consulted | 2 ( 1.3) | 3 ( 2.0) | 0.795 (0.525 : 1.427) |
Admitted to a health facility >24 hours** | 1 ( 0.7) | 1 ( 0.7) | 0.997 (0.517 : 1.691) |
Surgical procedure since delivery*** | 0 | 1 ( 0.7) | --- |
Retained placenta | 3 ( 2.0) | 2 ( 1.3) | 1.200 (0.581 : 2.477) |
Blood transfusion after delivery | 0 | 0 | --- |
Use of additional uterotonics (n, %) | 3 (2.0) | 4 (2.7) | 0.745 (0.189 : 2.928) |
Self-reported side effects (n, %)† | |||
Shivering/chills after birth | 75 (51.0) | 40 (27.8) | 1.594 (1.277 : 1.991) |
Fever after birth | 40 (27.2) | 21 (14.6) | 1.410 (1.121 : 1.772) |
Diarrhoea within 24 hours | 4 ( 2.7) | 1 ( 0.7) | 1.600 (1.017 : 2.518) |
Neonatal Death (n, %) | 0 | 3 ( 2.0) | --- |
If ‘yes, when did the baby die? (n, %) | |||
Before birth | 0 | 1 (33.3) | --- |
Within 24 hours of birth | 0 | 0 | |
More than 24 hours after birth | 0 | 2 (66.7) |