Pregnancy | Delivery | Postpartum | |||||
---|---|---|---|---|---|---|---|
10 weeks | 24-28 weeks | 32-34 weeks | 6 weeks | 6 months | 1 year | ||
Aim #1: Gestational Weight Gain (GWG) and Postpartum Weight Loss | |||||||
GWG (kg) | X | X | X | X | |||
Rate of GWG | X | X | X | X | |||
Compliance with IOM guidelines | X | X | X | X | |||
Area under the GWG curve (AUC) | X | X | X | X | |||
Postpartum weight loss | X | X | X | X | X | ||
Physical activity (actigraph, PPAQ) | X | X | X | X | X | X | |
Dietary intake (Hispanic FFQ) | X | X | X | X | X | X | |
Aim #2: Glycemia and Associated Biomarkers of Insulin Resistance | |||||||
Glucose (mg/dl) | X | X | X | X | X | X | |
Insulin (pmol/l) | X | X | X | X | X | X | |
Hb A1 c (%) | X | X | X | X | X | X | |
Adiponectin (μg/ml) | X | X | X | X | X | X | |
Leptin (ng/ml) | X | X | X | X | X | X | |
HOMA | X | X | X | X | X | X | |
Aim #3: Postpartum Biomarkers of Cardiovascular Disease Risk | |||||||
Total cholesterol (mg/dL) | X | X | X | X | |||
Triglycerides (mg/dL) | X | X | X | X | |||
HDL-cholesterol (mg/dL) | X | X | X | X | |||
LDL-cholesterol (mg/dL) | X | X | X | X | |||
Systolic blood pressure (mm Hg) | X | X | X | X | X | X | |
Diastolic blood pressure (mm Hg) | X | X | X | X | X | X | |
hsCRP (mg/dl) | X | X | X | X | |||
Aim #4: Offspring Outcomes | |||||||
Birthweight-for-gestational age z-score [fetal growth] | X | ||||||
Ponderal Index (g/cm3) | X | X | X | X | |||
Weight-for-length z-score (WFL-z) | X | X | X | X | |||
Weight-for-age z-score (WFA-z) | X | X | X | X | |||
Length-for-age z score (LFA-z) | X | X | X | X | |||
Sum of skinfolds, ratio of skinfolds | X | X | X | X | |||
Waist circumference (cm) | X | X | X | X | |||
Head circumference (cm) | X | X | X | X | |||
Aim #5: Cost Effectiveness Variables | |||||||
Star-up costs, total cost/participant | X | X | X | X | X | X | X |
Avg $/avg incremental improvement | X | X | X | X | X | X | X |
Covariates | |||||||
Clinical characteristics of current pregnancy | X | X | X | ||||
Medical history | X | ||||||
Sociodemographic factors | X | ||||||
Smoking (cotinine) and substance use | X | X | X | X | X | X | |
Depression | X | X | X | X | X | X | |
Sleep | X | X | X | X | X | X | |
Breastfeeding | X | X | X | ||||
Social Support | X | X | X | X | X | X |