Figure 1

Heat Maps and Volcano plots of two comparisons. (A) Heat Maps: Differentially expressed lncRNAs for non-rupture of membrane vs. rupture of membrane (AB vs. CD) and preterm labor vs. full-term labor (AC vs. BD) were hierarchically clustered. “Red” indicates high relative expression, and “blue” indicates low relative expression. (B) Volcano Plots of two comparisons: X-axis is fold change (log 2) and Y-axis is p value (−log 10). Up-regulated (X axis > 0) or down-regulated (X axis < 0) lncRNAs (red squares) were identified in about the same number when fold change was set >2 folds [Log 2 (Fold change)] in PTB vs. PPROM.