Table 5 Percent distribution of Active Pharmaceutical Ingredient (API) in purchased ampoules of oxytocin and methylergometrine, by district
| Â | Karnataka state | Uttar Pradesh state | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Bagalkot | Hassan | Agra | Gorakhpur | ||||
% API | OXYTOCIN (%) | METHYL-ERGOMETRINE (%) | OXYTOCIN (%) | METHYL-ERGOMETRINE (%) | OXYTOCIN (%) | METHYL- ERGOMETRINE (%) | OXYTOCIN (%) | METHYL- ERGOMETRINE (%) |
0%-25% | 0.0 | 0.0 | 8.9 | 0.0 | 2.0 | 2.0 | 0.0 | 2.0 |
26-50% | 0.0 | 9.5 | 2.2 | 0.0 | 6.0 | 2.0 | 0.0 | 0.0 |
51%-75% | 4.2 | 7.1 | 4.4 | 13.0 | 14.0 | 8.0 | 2.0 | 6.0 |
76%-89% | 27.1 | 83.3 | 22.2 | 82.6 | 16.0 | 42.0 | 10.0 | 36.0 |
WITHIN MANU-FACTURER SPECIFICA-TION (90%-110%) | 66.7 | 0.0 | 60.0 | 4.3 | 50.0 | 46.0 | 78.0 | 56.0 |
111%-120% | 2.1 | 0.0 | 2.2 | 0.0 | 12.0 | 0.0 | 8.0 | 0.0 |
Missing data | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 |
TOTAL | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
% Out of specification | 33.0 | 100.0 | 40.0 | 95.7 | 50.0 | 54.0 | 22.0 | 44.0 |
Median API | 98.5 | 84.4 | 98.7 | 85.8 | 99.0 | 89.2 | 102.9 | 90.4 |
N of ampoules of analysis | 48 | 42 | 45 | 46 | 50 | 50 | 50 | 50 |