Pregnancy time point | Prophylactic dose prescribed | Treatment dose prescribed | ||
---|---|---|---|---|
 | N | Median concentration in ug/ml (inter-quartile range) | N | Median concentration in ug/ml (inter-quartile range) |
First trimester | 64 | 335 | 24 | 270 |
(270-487) | (230-422) | |||
Second trimester | 193 | 620 | 47 | 480 |
(465-955) | (350-1180) | |||
Third trimester | 225 | 1020 | 62 | 850 |
(735-1625) | (545-1270) | |||
Within a week of delivery | 79 | 2360 | 23 | 1610 |
(1790-4130) | (440-2450) | |||
≥ 8 weeks postpartum | 78 | 365 | 20 | 260 |
(256-525) | (220-325) |