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Table 4 Thrombin generation variation between the Caucasian and African-Caribbean groups

From: Changes in thrombin generation and D-dimer concentrations in women injecting enoxaparin during pregnancy and the puerperium

Parameter

Ethnicity

1 sttrimester

2 ndtrimester

3 rdtrimester

Within one week of delivery

≥ 8 weeks postpartum

  

N = 34 v 8

N = 67 v 24

N = 75 v 27

N = 45 v 23

N = 47 v 24

Lag time (min)

Caucasian

4.11 (1.74)

3.49 (0.83)

3.62 (0.98)

3.03 (1.09)

2.98 (0.57)

A-C

3.27 (0.81)

3.18 (0.74)

3.34 (0.77)

2.73 (0.61)

2.72 (0.51)

ETP (nmol/L.min)

Caucasian

1296 (651)*

1806 (557)*

1784 (451)

1944 (578)

1306 (356)

A-C

2126 (754)

2129 (556)

1810 (432)

1911 (540)

1402 (336)

Peak height (nmol/L)

Caucasian

193 (124)*

284 (114)*

280 (92)

379 (119)

256 (60)

A-C

323 (146)

356 (112)

301 (96)

367 (91)

286 (63)

tt Peak (min)

Caucasian

8.27 (3.6)

6.83 (1.8)*

6.95 (1.9)

5.23 (1.6)

5.65 (0.9)*

A-C

6.61 (2.2)

5.89 (1.3)

6.22 (1.6)

4.88 (1.0)

5.15 (0.9)

Start tail (min)

Caucasian

27.94 (7.4)

26.37 (4.3)

26.07 (4.7)

24.29 (3.8)

20.42 (2.7)

A-C

28.10 (3.1)

26.73 (3.9)

25.93 (4.2)

24.40 (4.1)

20.69 (2.8)

  1. *Significance at <0.05 level; A-C refers to the African-Caribbean population, C refers to Caucasian population. N = number of samples in each trimester (Caucasian vs African-Caribbean). Mean with SD in brackets presented.