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Table 3 Health outcomes for infants exposed to antenatal corticosteroids versus those not exposed

From: Use of antenatal corticosteroids prior to preterm birth in four South East Asian countries within the SEA-ORCHID project

 

Antenatal

corticosteroids

   
 

Exposed

Not exposed

Comparative statistic#

95% CI

p-value

All babies

n = 114

n = 152

   

Gestational age at birth*‡ (weeks.days)

30.4 (2.6)

29.9 (2.7)

0.47

-0.19; 1.13

0.16

Birth weight*‡ (kg)

1.62 (0.65)

1.48 (0.63)

0.14

-0.02; 0.29

0.08

Stillbirth

2 (2)

42 (28)

0.06

0.02; 0.25

0.01

All deaths (stillbirths/deaths prior to discharge)

18 (16)

49 (32)

0.49

0.30; 0.79

0.01

Mode of birth

    

0.01

normal vaginal

59 (52)

99 (65)

1

--

--

vaginal breech

4 (4)

19 (13)

0.39

0.14; 1.11

0.06

operative vaginal birth

2 (2)

2 (1)

1.65

0.24; 11.45

0.63

caesarean section

49 (43)

32 (21)

1.85

1.28: 2.67

0.01

Live born babies

n = 112

n = 111

   

Live born babies discharged alive

96 (86)

103 (93)

0.92

0.84; 1.0

0.05

Respiratory distress syndrome ‡‡

59 (60)

54 (57)

1.06

0.83; 1.34

0.64

Severity of lung disease§

    

0.01

none

22 (30)

4 (11)

1

--

--

mild

7 (9)

15 (42)

--

--

--

moderate

27 (37)

6 (17)

--

--

--

severe

18 (24)

11 (30)

--

--

 

Use of oxygen therapy¶

50 (50)

55 (57)

0.86

0.66; 1.12

0.27

Use of mechanical ventilation¶

53 (54)

25 (39)

1.38

0.97; 1.98

0.06

Apgar Score < 7 at 1 min †

42 (38)

57 (52)

0.73

0.54; 0.98

0.04

Apgar Score < 7 at 5 min †

15 (14)

34 (31)

0.44

0.25; 0.75

0.01

  1. Figures are numbers with percentages rounded to the nearest whole number in brackets and with relative risk and 95% confidence intervals as the comparative statistic#, or *mean and standard deviation with mean difference between groups and 95% confidence intervals as the comparative statistic#. §Severity of lung disease is defined as none (no oxygen required), mild (Oxygen < 40% FiO2), moderate (FiO2 40–79%), severe (FiO2 80% or more). ‡Values are based on 114 in the Exposed Group and 151 in the Not Exposed Group. ‡‡ Values are based on 98 in the Exposed Group and 95 in the Not Exposed Group. ¶Values are based on 101 in the Exposed group and 96 in the Not Exposed Group. ¶P Values are based on 98 in the Exposed Group and 64 in the Not Exposed Group. † Values are based on 111 in the Exposed Group and 110 in the Not Exposed Group.