Skip to main content

Table 2 Estimated crude reduction in maternal mortality due to micronutritional supplementation and presumptive treatment of infection, by cause of maternal death.

From: Could a simple antenatal package combining micronutritional supplementation with presumptive treatment of infection prevent maternal deaths in sub-Saharan Africa?

Cause of maternal death Proportion of all maternal deaths (range)1 Intervention Effectiveness of intervention – reduction in deaths by cause (95% CI)2 Crude reduction in all-cause maternal mortality3 Maternal deaths prevented per year4
Severe hypertensive disorders 9.1% (3.9–21.9) calcium supplementation 20% (3–35) 0.1–7.7% 300–19,200
Puerperal sepsis 9.7% (6.3–12.6) anti-microbial prophylaxis 51% (0–77) 0.0–9.7% 0–24,300
Anemia 3.7% (0.0–13.2) anti-malarial prophylaxis 38% (22–50) 0.0–1.2%5 0–3,000
   iron supplementation 67% (31–84) 0.0–6.4%6 0–15,900
  1. 1 Source: WHO systematic review of causes of maternal deaths [9].
  2. 2 Source: Cochrane Reviews [19,22,24,26].
  3. 3 Calculated using Equation 1.
  4. 4 Assuming 250,000 deaths per year in sub-Saharan Africa [8].
  5. 5 Assuming 18% of maternal deaths caused by anemia are attributable to P falciparum infection [12].
  6. 6 Assuming 30–70% of non-malarial maternal deaths caused by anemia are attributable to iron deficiency [12-17].