Table 1 Participant characteristics
From: Metabolic Syndrome features and risk of neural tube defects
Maternal characteristic | Cases of women with an NTD-affected pregnancy (n = 89) | Controls of women without an NTD-affected pregnancy (n = 434) | P-value, comparing cases and controls |
|---|---|---|---|
Mean (SD) age, years | 28.6 (4.8) | 29.8 (5.1) | 0.04 |
Median gravidity | 2.0 | 2.0 | 0.02 |
Weight, kg | |||
Mean (SD) | 68.6 (15.5) | 67.4 (13.5) | 0.50 |
90th centile | 87.6 | 83.9* | 0.50 |
No. (%) with prepregnancy diabetes mellitus | 3 (3.4) | 5 (1.2) | 0.14 |
Ethnicity (No. [%]) | |||
White | 56 (70.9) | 367 (85.8) | 0.01 |
Asian | 16 (20.2) | 41 (9.6) | |
Black | 5 (6.3) | 12 (2.8) | |
Other | 2 (2.5) | 8 (1.9) | |
Mean (SD) % with low income status in the local population | 12.9 (6.7) | 13.2 (7.5) | 0.77 |
Geometric mean (SD) serum folate, nmol/L | 13.3 (3.0) | 13.9 (2.8) | 0.96 |
Serum highly sensitive C-reactive protein, mg/L | |||
Geometric mean (SD) | 6.1 (2.9) | 6.4 (2.3) | 0.92 |
75th centile | 13.0 | 11.5* | -- |