From: Prediction of pre-eclampsia: a protocol for systematic reviews of test accuracy
History | Risk factors e.g. nulliparity, new partner, hypertension on oral contraceptives, pre-existing diabetes, renal disease, chronic hypertension, parity |
Examination | Blood pressure (systolic and diastolic and mean arterial pressure), peripheral oedema, body mass index, waist circumference, hip:waist ratio |
Investigations | Â |
Biochemical | Serum uric acid, urinary calcium excretion, urinary albumin-creatinine and calcium-creatinine ratios, microalbuminuria, fibronectin, spot proteinuria, 24-hour urinary protein levels |
Haemodynamic | Pressor response to various forms of stimuli e.g., supine "rollover", isometric exercise, passive tilting, uterine artery Doppler |
Haematological | Antithrombin III, platelet count, haemoglobin, haematocrit, fibrinogen |
Other tests | Thrombomodulin, endothelin-1, plasminogen activator inhibitor, free fatty acids, atrial natriuretic peptide, angiotensin II infusion, platelet angiotensin II binding site density, öhCG, õFP, fasting insulin levels |