From: Cerebral palsy and placental infection: a case-cohort study
CHARACTERISTICS | Cases n (%) | Sub-Cohort n (%) | Relative risk (95% Confidence Intervals) | P value |
---|---|---|---|---|
Total | 82 | 207 | Â | Â |
Obstetric Factors | Â | Â | Â | Â |
Primigravida | 27 (33%) | 81 (39%) | 0.81 [0.55, 1.19] | 0.29 |
Threatened preterm labor | 15 (18%) | 18 (9%) | 1.82 [1.21, 2.73] | < 0.01 |
Pre-eclampsia | 8 (10%) | 30 (14%) | 0.69 [0.36, 1.30] | 0.25 |
Severe intra-uterine growth restriction (as in casenotes) | 13 (16%) | 32 (16%) | 1.00 [0.61, 1.64] | 1.00 |
Placental abruption | 11 (13%) | 19 (9%) | 1.37 [0.83, 2.24] | 0.22 |
Preterm prelabor rupture of the membranes | 32 (39%) | 79 (38%) | 1.02 [0.71, 1.48] | 0.90 |
Placenta previa | 6 (7%) | 8 (4%) | 1.53 [0.83, 2.83] | 0.18 |
Preterm labor | 37 (45%) | 94 (45%) | 1.04 [0.72, 1.49] | 0.83 |
Mode of delivery | Â | Â | Â | Â |
   Normal vaginal delivery | 25 (30%) | 56 (27%) | 1.00 | 0.37 |
   Cesarean section | 47 (57%) | 129 (62%) | 0.83 [0.56, 1.24] |  |
   Forceps/Breech | 10 (12%) | 22 (11%) | 1.08 [0.60, 1.94] | 0.79 |
Neonatal Factors | Â | Â | Â | Â |
Gestational age at delivery | Â | Â | Â | Â |
   ≤ 27 weeks | 28 (34%) | 54 (26%) | 1.87 [0.94, 3.70] | 0.07 |
   28–31 weeks | 46 (56%) | 121 (58%) | 1.47 [0.75, 2.85] | 0.26 |
   ≥ 32 weeks | 8 (10%) | 32 (16%) | 1.00 |  |
Gestational age at delivery weeks, median (inter-quartile range) | 29 (27–30) | 29 (27–31) | 0.93 [0.86, 1.00]a | 0.06 |
Birthweight, grams, median (inter-quartile range) | 1100 (880–1290) | 1170 (970–1350) | 0.93 [0.87, 0.99]b | 0.03 |
Multiple gestation | 18 (22%) | 58 (28%) | 0.77 [0.49, 1.20] | 0.25 |
Male gender | 48 (59%) | 104 (50%) | 1.30 [0.90, 1.89] | 0.16 |