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Table 1 Maternal, pregnancy and delivery variables, by mode of conception (n = 2529)

From: Mortality and major morbidities in very preterm infants born from assisted conception or naturally conceived: results of the area-based ACTION study

 

Non-AC

AC

p-value

 

n

(%)

n

(%)

 

Age ≥35 years

703

(31.9)

69

(45.4)

<0.001

Country of origin other than Italy

541

(23.2)

16

(9.9)

<0.001

Upper secondary/university education

1206

(59.6)

108

(78.3)

<0.001

Previous births

937

(40.4)

30

(18.5)

<0.001

Plurality

     

 Twin

264

(11.6)

75

(46.0)

 

 Triplet

14

(0.6)

42

(25.8)

<0.001

 Quadruplet

0

 

2

(1.2)

 

Complications of pregnancy

     

 Disorders of placentation1

731

(31.4)

46

(28.4)

0.431

 Inflammation/infection2

1446

(61.9)

109

(67.3)

0.170

Gestational age at delivery (weeks)

    

 <26

345

(14.6)

28

(17.2)

0.606

 26-27

412

(17.4)

23

(14.1)

 

 28-29

591

(25.0)

39

(23.9)

 

 30-31

1018

(43.0)

73

(44.8)

 

Delivery at tertiary centre

2108

(89.1)

154

(94.5)

0.031

Any antenatal steroids

1741

(76.4)

131

(81.9)

0.111

Spontaneous onset of labour

1014

(43.8)

84

(52.8)

0.027

Caesarean delivery

1687

(71.6)

130

(79.7)

0.025

  1. 1Disorders of placentation include: pregnancy hypertension disorders, HELLP syndrome, pre-eclampsia, eclampsia, foetal growth restriction.
  2. 2Inflammation/infection disorders include: threatened preterm labor, PPROM, antepartum haemorrhage, maternal infection.