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Table 2 Frequency of the investigated cell surface and intracellular markers

From: B7 costimulation and intracellular indoleamine-2,3-dioxygenase (IDO) expression in peripheral blood of healthy pregnant and non-pregnant women

 

Non-pregnant women (n = 14)

Healthy pregnant women (n = 20)

CD3+ CD28+ cells/CD3+ lymphocytes

76.0 (64.7-82.9)%

88.4* (81.8-90.6)%

CD3+ CD28+ CD152+ cells/CD3+ CD28+ lymphocytes

8.90 (7.57-11.4)%

6.64* (5.07-9.89)%

CD3+ CD278+ cells/CD3+ lymphocytes

55.7 (49.5-56.7)%

89.9* (75.7-91.6)%

CD3+ CD279+ cells/CD3+ lymphocytes

46.3 (39.3-51.2)%

51.9* (47.9-67.7)%

CD4+ CD28+ cells/CD4+ lymphocytes

97.8 (96.7-98.8)%

97.3 (93.0-99.2)%

CD4+ CD28+ CD152+ cells/CD4+ CD28+ lymphocytes

6.92 (4.93-8.63)%

5.61 (3.65-9.09)%

CD4+ CD278+ cells/CD4+ lymphocytes

56.7 (52.8-59.5)%

87.7* (76.3-92.2)%

CD4+ CD279+ cells/CD4+ lymphocytes

49.4 (42.1-54.5)%

44.2 (37.5-65.2)%

CD11b + CD80+ cells/CD11b + monocytes

55.5 (17.3-69.8)%

17.6* (13.6-25.4)%

CD11b + CD86+ cells/CD11b + monocytes

23.8 (17.3-29.5)%

20.7 (14.9-31.9)%

CD11b + CD274+ cells/CD11b + monocytes

78.4 (70.3-85.9)%

80.7 (77.2-87.8)%

CD11b + CD275+ cells/CD11b + monocytes

63.8 (59.0-72.1)%

17.3* (14.1-27.0)%

CD3+ IDO + cells/CD3+ lymphocytes

5.90 (2.65-16.9)%

24.1* (13.3-56.4)%

IDO mean fluorescence intensity in CD3+ IDO + cells (arbitrary unit)

9888 (7482–11475)

62500* (19800–84475)

CD11b + IDO + cells/CD11b + monocytes

2.59 (1.99-11.7)%

22.5* (13.6-50.5)%

IDO mean fluorescence intensity in CD11b + IDO + cells (arbitrary unit)

21400 (19075–23875)

70450* (38775–114000)

  1. *p < 0.05 versus non-pregnant women. Data are presented as median (interquartile range). IDO – indoleamine-2,3-dioxygenase, MFI – mean fluorescence intensity.