Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: multiple courses of antenatal corticosteroids for preterm birth study at 5 years of age (MACS-5)

Table 5 Adjusted odds ratios, confidence limits and p -values by gestational age at birth

Outcome	Gestational age at birth	OR [ 95% confidence limits]	p-value	p-value for interaction
Death or severe disability^a	< 30 weeks	0.85 [0.35, 2.11]	0.608	0.064
	30-36 weeks	0.84 [0.52, 1.36]	0.262
	≥ 37 weeks	1.69 [1.04, 2.77]	0.037*
Neurosensory disability^b	< 30 weeks	0.85 [0.35, 2.11]	0.732	0.021
	30-36 weeks	0.84 [0.52, 1.36]	0.481
	≥ 37 weeks	3.70 [1.57, 8.75]	0.004*
Neurocognitive^c	< 30 weeks	0.84 [0.35, 2.01]	0.698	0.605
	30-36 weeks	0.91 [0.61, 1.36]	0.632
	≥ 37 weeks	1.31 [0.75, 2.29]	0.347
Death^d	< 30 weeks	1.10 [0.54, 2.24]	0.794	0.587
Death^d	30-36 weeks	0.68 [0.35, 1.31]	0.247	0.587
	≥ 37 weeks	sparse data, no convergence

^aadjusted for gestational age at randomization, premature rupture of membranes, maternal smoking, parity and the country’s perinatal mortality rate.
^badjusted for gestational age at randomization and premature rupture of membranes.
^cadjusted for gestational age at randomization, multiple pregnancy, maternal smoking, sex of the baby and the country’s perinatal mortality rate.
^dadjusted for gestational age at randomization, premature rupture of membranes, parity and the country’s perinatal mortality rate.

ISSN: 1471-2393