Table 1 Characteristics at randomization into MACS by gestational age at delivery
Characteristic | Preterm (<30 weeks) N = 158 women | Preterm (30–36 weeks) N = 781 women | Term (≥37 weeks) N = 437 women |
|---|---|---|---|
Mean maternal age (years) (SD) | 29.3 (6.3) | 29.8 (6.2) | 28.1 (6.2) |
Treatment group | |||
Single course | 76 (48.1%) | 375 (48.0%) | 236 (54.0%) |
Repeat courses | 82 (51.5%) | 406 (52%) | 201 (46.0%) |
Multiple pregnancy | 37 (23.4%) | 244 (31.2%) | 26 (5.9%) |
Number of fetuses | |||
Singleton | 121 (77%) | 537(69%) | 411 (94%) |
Twin | 29 (18%) | 197 (25%) | 25 (6%) |
Triplet | 8 (5%) | 47 (6%) | 1 (<0.01%) |
Mean gestational age at randomization (weeks) (SD) | 27.2 (1.1) | 29.7 (1.9) | 29.6 (1.9) |
Gestational age at randomization (weeks) | |||
< 25 | 0 (0%) | 0 (0%) | 0 (0%) |
25-27 | 114 (72%) | 163 (21%) | 91 (21%) |
28-32 | 44 (28%) | 618 (79%) | 334 (79%) |
> 32 | 0 (0%) | 0 (0%) | 2 (<0.01%) |
Preterm pre-labor rupture of membranes at randomization | 77 (49%) | 138 (18%) | 8 (1.8%) |
National perinatal mortality rate of countryb | |||
≤ 10/1000 | 127(80%) | 553 (71%) | 224 (51%) |
> 10 - 20/1000 | 22 (14%) | 187 (24%) | 175 (40%) |
> 20/1000 | 9 (6%) | 41 (5%) | 38 (9%) |
Number of previous pregnancies | |||
0 | 50 (32%) | 245 (31%) | 103 (24%) |
1-4 | 91 (57%) | 465 (60%) | 287 (66%) |
>4 | 17 (11%) | 70 (9%) | 45 (10%) |
Missing | 1 (<0.01%) | 2 (<0.01%) | |
Maternal smoking | 15 (9%) | 64 (8%) | 62 (14%) |
Number of courses of study drug | |||
0 | 2 (1.2%) | 3 (<0.01%) | 1 (<0.01%) |
1 | 128(81%) | 312 (40%) | 109 (25%) |
2 | 26 (16%) | 225 (33%) | 156 (36%) |
3 | 1 (0.1%) | 133 (17%) | 103 (24%) |
4 | 0 (0%) | 78 (10%) | 68 (16%) |
Missing | 1 (0.1%) | 0 (0%) | 0 (0%) |