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Table 1 Characteristics at randomization into MACS by gestational age at delivery

From: Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: multiple courses of antenatal corticosteroids for preterm birth study at 5 years of age (MACS-5)

Characteristic Preterm (<30 weeks) N = 158 women Preterm (30–36 weeks) N = 781 women Term (≥37 weeks) N = 437 women
Mean maternal age (years) (SD) 29.3 (6.3) 29.8 (6.2) 28.1 (6.2)
Treatment group    
Single course 76 (48.1%) 375 (48.0%) 236 (54.0%)
Repeat courses 82 (51.5%) 406 (52%) 201 (46.0%)
Multiple pregnancy 37 (23.4%) 244 (31.2%) 26 (5.9%)
Number of fetuses    
Singleton 121 (77%) 537(69%) 411 (94%)
Twin 29 (18%) 197 (25%) 25 (6%)
Triplet 8 (5%) 47 (6%) 1 (<0.01%)
Mean gestational age at randomization (weeks) (SD) 27.2 (1.1) 29.7 (1.9) 29.6 (1.9)
Gestational age at randomization (weeks)    
< 25 0 (0%) 0 (0%) 0 (0%)
25-27 114 (72%) 163 (21%) 91 (21%)
28-32 44 (28%) 618 (79%) 334 (79%)
> 32 0 (0%) 0 (0%) 2 (<0.01%)
Preterm pre-labor rupture of membranes at randomization 77 (49%) 138 (18%) 8 (1.8%)
National perinatal mortality rate of countryb    
≤ 10/1000 127(80%) 553 (71%) 224 (51%)
> 10 - 20/1000 22 (14%) 187 (24%) 175 (40%)
> 20/1000 9 (6%) 41 (5%) 38 (9%)
Number of previous pregnancies    
0 50 (32%) 245 (31%) 103 (24%)
1-4 91 (57%) 465 (60%) 287 (66%)
>4 17 (11%) 70 (9%) 45 (10%)
Missing   1 (<0.01%) 2 (<0.01%)
Maternal smoking 15 (9%) 64 (8%) 62 (14%)
Number of courses of study drug    
0 2 (1.2%) 3 (<0.01%) 1 (<0.01%)
1 128(81%) 312 (40%) 109 (25%)
2 26 (16%) 225 (33%) 156 (36%)
3 1 (0.1%) 133 (17%) 103 (24%)
4 0 (0%) 78 (10%) 68 (16%)
Missing 1 (0.1%) 0 (0%) 0 (0%)
  1. a1 child lost to follow-up case earlier in trial found and included at 5 years, no maternal data available.
  2. bCountries with a national perinatal mortality rate of ≤10/1000 were: Canada, Chile, Denmark, Germany, Hungary, Israel, the Netherlands, Poland, Spain, Switzerland, United Kingdom, United States; countries with a national perinatal mortality rate of >10 - 20/1000 were: Argentina, Brazil, Peru; countries with a national perinatal mortality rate of >20/1000 were: Bolivia, China, Colombia, Jordan, Russia.