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Figure 2 | BMC Pregnancy and Childbirth

Figure 2

From: Prostaglandin pathway gene expression in human placenta, amnion and choriodecidua is differentially affected by preterm and term labour and by uterine inflammation

Figure 2

Expression of prostaglandin pathway genes in pregnant human uterine tissues. (A) Relative levels of mRNA by ΔΔCt method following qPCR, log10-transformed, shown as mean ± SD. A, amnion (blue); C, choriodecidua (red); P, placenta (green). PNIL, preterm not-in-labour; SPL, spontaneous preterm labour; TNIL, term not-in-labour; STL, spontaneous term labour; IOL, induction of labour; INF, inflammation. Numbers of samples: PNIL = 4; SPL = 4; TNIL = 6; STL = 5; IOL = 5; INF = 4. (B) Statistical comparisons of gene expression. Relationships with gestational age (g. age) in combined not-in-labour (NIL = PNIL + TNIL) and spontaneous labour (SL = SPL + STL) groups, and with duration of labour (SPL + STL + IOL) tested by correlation (Pearson’s); level of significance and direction of correlation are indicated. Comparisons between the presence and absence of labour (preterm and term) and inflammation were tested by Student’s t-tests.

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