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Table 2 Crude and adjusted odds ratios of developing offspring macrosomia

From: The role of gestational diabetes, pre-pregnancy body mass index and gestational weight gain on the risk of newborn macrosomia: results from a prospective multicentre study

 

Macrosomia (birthweight >4000 g)

(%)

Crude OR

p-value

Adjusted OR

p-value

 

(95% CI)

 

(95% CI)

 

Pre-gestational BMI*

     

18.5-24.9

(6.9)

1

 

1

 

<18.5

(2.8)

0.4 (0.3 - 0.6)

<0.001

0.5 (0.3-0.7)

<0.001

25-29.9

(10.4)

1.6 (1.3 - 1.8)

<0.001

1.1 (0.9-1.3)

0.319

≥30

(15.7)

2.5 (2.0 - 3.1)

<0.001

1.7 (1.4-2.2)

<0.001

Gestational weight gain

     

Recommended by IOM

(6.5)

1

 

1

 

< Recommended by IOM

(4.1)

0.6 (0.5 - 0.7)

<0.001

0.6 (0.5-0.8)

<0.001

> Recommended by IOM

(12.6)

2.1 (1.8 - 2.4)

<0.001

1.9 (1.6-2.2)

<0.001

Parity

     

Primiparous

(5.8)

1

 

1

 

Multiparous

(9.6)

1.7 (1.5 - 1.9)

<0.001

2.0 (1.7-2.3)

<0.001

Maternal Diabetes

     

No

(7.4)

1

 

1

 

Gestational diabetes

(14.2)

2.1 (1.5 - 2.8)

<0.001

2.1 (1.5-3.0)

<0.001

Pre-gestational diabetes

(16.7)

2.5 (1.0 - 6.1)

0.032

3.0 (1.2-7.6)

0.023

Maternal height (cm)

     

≤165

(5.6)

1

 

1

 

>165

(9.7)

1.8 (1.6 - 2.1)

<0.001

1. 9 (1.6-2.2)

<0.001

Gestational age (weeks)

     

37-40

(5.4)

1

 

1

 

>40

(16.9)

3.5 (3.1 - 4.0)

<0.001

3. 7 (3.2-4.2)

<0.001

Neonate sex

     

Female

(5.0)

1

 

1

 

Male

(10.1)

2.1 (1.9 - 2.4)

<0.001

2.2 (2.0-2.6)

<0.001

  1. *Test for Trend: p <0.001.