Table 2 Data items collected for the study and source

Data collected specifically for this study

Name, date of birth, address, postcode

Baseline questionnaire, RADIS2

NHS number

Employment status

Baseline questionnaire

Smoking and alcohol use

Obstetric history

Weight

RADIS2 or paper proforma

Height

BMI

Presence or absence of the following markers:

Cardiac Echogenic Foci, Choroid Plexus Cyst, Echogenic Bowel, Mild Ventriculomegaly, Nuchal Thickening, Short Femur, Pelvicalyceal Dilatation

Routinely collected data

Pregnancy outcome, live birth, stillbirth, gestation at birth, birth weight, neonatal death, infant death

NCCHD and AWPS

Presence of any structural abnormality, congenital malformation or cystic fibrosis

CARIS

Cytogenetic information

Cardiff and Vale Cytogenetic laboratory, CARIS

Down’s syndrome risk

NHS Biochemistry laboratory