Characteristics | Overall | Severe preeclampsia | Eclampsia | p |
---|---|---|---|---|
n | 54 | 37 | 17 | |
Age, years (SD) | 26.3 (6.6) | 27.6 (6.5) | 23.3 (5.9) | 0.025 |
Married (%) | 23 (42.6) | 17 (45.9) | 6 (35.3) | 0.56 |
Weight, kg (SD) | 76.9 (14.6) | 78.4 (14.4) | 73.6 (14.8) | 0.27 |
Body mass index, Kg/m2 (SD) | 26.3 (4.8) | 26.7 (4.7) | 25.4 (5.2) | 0.37 |
Systolic blood pressure, mmHg (SD) | 167.2 (19.6) | 166.6 (16.9) | 168.7 (25.1) | 0.71 |
Diastolic blood pressure, mmHg (SD) | 104.1 (17.6) | 104.6 (17.2) | 102.9 (19.0) | 0.75 |
Personal history, n (%) | 9 (16.7) | 9 (24.3) | 0 | 0.044 |
Family history, n (%) | 2 (3.7) | 2 (5.4) | 0 | >0.99 |
Gravidity, median (min-max) | 1 (1–3) | 2 (1–4) | 1 (1–1) | 0.018 |
Para, median (min-max) | 1 (0–2) | 1 (1–2) | 1 (0–1) | 0.007 |
Premature, median (min-max) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0.72 |
Aborted, median (min-max) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0.88 |
Alive, median (min-max) | 1 (1–2) | 1 (1–3) | 1 (1–1) | 0.0005 |
Primipartenity, n (%) | 37 (68.5) | 22 (59.4) | 15 (88.2) | 0.06 |
Single gestation, n (%) | 49 (90.1) | 34 (9.9) | 15 (88.2) | 0.64 |
Gestational age at diagnosis, week (SD) | 34.3 (6.0) | 34.8 (5.8) | 33.3 (6.5) | 0.42 |
Gestational age at delivery, week (SD) | 36.9 (3.5) | 37.6 (2.8) | 35.4 (4.2) | 0.028 |
Delivery – diagnosis time, day (median, min-max) | 0 (0–20) | 0 (0–20) | 0 (0–17) | 0.18 |
Time to delivery from diagnosis >1 week, n (%) | 14 (25.9) | 11 (29.7) | 3 (17.6) | 0.51 |
Vaginal delivery, n (%) | 31 (57.4) | 20 (54) | 11 (64.7) | 0.56 |
Birth weight, g (SD) | 2732 (691) | 2938 (586) | 2286 (708) | 0.0008 |
Foetal outcome, n (%) | <0.0001 | |||
Death | 10 (18.5) | 2 (5.4) | 8 (47) | |
Alive | 44 (81.5) | 35 (94.6) | 9 (53) | |
Treatment received | ||||
Methyl-dopa tablet, n (%) | 47 (87) | 31 (83.8) | 16 (94.1) | 0.41 |
Nicardipine injection, n (%) | 35 (64.8) | 19 (51.3) | 16 (94.1) | 0.002 |
Nicardipine tablet, n (%) | 32 (59.2) | 23 (62.2) | 9 (52.9) | 0.56 |
Labetalol tablet, n (%) | 4 (7.4) | 3 (8.1) | 1 (5.9) | >0.99 |
Diazepam injection, n (%) | 5 (9.2) | 0 | 5 (29.4) | 0.002 |
Clorazepam tablet, n (%) | 10 (18.5) | 4 (10.8) | 6 (35.3) | 0.06 |
MgSO4 injection, n (%) | 54 (100) | 37 (100) | 17(100) | NA |
Outcomes | ||||
Persisting hypertension at M3, n (%) | 15 (27.8) | 11 (29.7) | 4 (23.5) | 0.75 |
Persisting hypertension at M6, n (%) | 8 (14.8) | 6 (16.2) | 2 (11.8) | >0.99 |
Persisting proteinuria at M3, n (%) | 17 (31.5) | 8 (21.6) | 9 (52.9) | 0.03 |
Persisting proteinuria at M6, n (%) | 1 (1.8) | 1 (2.7) | 0 | >0.99 |
Persisting hypertension or proteinuria at M3, n (%) | 26 (48.1) | 16 (43.2) | 10 (58.8) | 0.38 |
Persisting hypertension or proteinuria at M6, n (%) | 9 (16.7) | 7 (18.9) | 2 (11.8) | 0.70 |