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Table 3 Obstetric and neonatal outcome

From: False positive morphologic diagnoses at the anomaly scan: marginal or real problem, a population-based cohort study

 

Total cohort

False positives

Misclassification

True positives

p1

 

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 
 

% [m ± SD]

% [m ± SD]

% [m ± SD]

% [m ± SD]

 

Year of birth

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

 2006

22.5

17.0

26.6

22.5

0.49

 2007

25.1

21.3

20.4

26.0

 

 2008

28.1

34.0

28.6

27.4

 

 2009

24.3

27.7

24.5

23.9

 

Female

(n = 526) 45.9

(n = 39) 44.7

(n = 49) 48.9

(n = 438) 45.7

0.89

Pregnancy outcome 2

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

 TOPFA< 21 weeks

2.3

0

4.2

2.3

0.39

 TOPFA ≥ 22 weeks

20.8

0

31.3

21.9

0.0001

 In utero fetal death

2.5

0

2.1

2.7

0.50

 Neonatal death

2.7

2.1

2.1

2.7

0.94

Term at birth (weeks)

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

[35.5 ± 6.1]

[39.4 ± 1.9]

[34.2 ± 6.5]

[35.2 ± 6.2]

0.001

Weight (g)

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

[2588 ± 1134]

[3272 ± 525]

[2265 ± 1211]

[2551 ± 1147]

0.001

IUGR (3 rd Percentile)

(n = 482)

(n = 39)

(n = 44)

(n = 399)

 

4.9

2.1

9.1

4.8

0.03

Height (cm)

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

[45.1 ± 7.7]

[49.3 ± 2.1]

[42.2 ±8.9]

[44.9 ±7.8]

0.001

Type of malformation

(n = 526)

(n = 39)

(n = 49)

(n = 438)

 

 Single

76.0

100

53.1

76.3

0.40

 Multiple

8.2

0

22.5

7.3

 

 Syndrome with normal karyotype

4.3

0

8.2

4.3

 

 Chromosomal anomalies

11.4

0

16.3

12.1

 
  1. 1Comparison of 3 groups: False positives, Misclassifications, True positives.
  2. 2TOPFA (Termination Of Pregnancy for Fetal Anomaly).