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Table 1 Magnesium sulphate vs placebo/no treatment: primary outcomes[33]

From: Magnesium sulphate at 30 to 34 weeks’ gestational age: neuroprotection trial (MAGENTA) - study protocol

Primary outcomes

RR, 95% CI

Number of trials; participants

Death or cerebral palsy

0.85, 0.74 to 0.98*

four trials; 4446 infants

Death (fetal and later)

0.95, 0.80 to 1.12

four trials; 4446 infants

Cerebral palsy

0.71, 0.55 to 0.91*

four trials; 4446 infants

Any neurological impairment

1.03, 0.87 to 1.21

one trial; 1255 infants

Death or substantial gross motor dysfunction

0.84, 0.71 to 1.00

three trials; 4387 infants

  1. *Significantly in favour of magnesium sulphate.