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Table 4 Logistic regression for tSNPs with significant genotype tests

From: Variation in endoglin pathway genes is associated with preeclampsia: a case–control candidate gene association study

White Subgroup
Gene/tSNP Genotype Groups OR 99% CI p-valuea
ENG: rs10121110 AA vs. GG 2.29 1.02 - 5.13 0.008
AG vs. GG 1.52 0.69 - 3.36 0.17
TGFBR2: rs6550005b GG vs. AA + GA 1.60 0.89 - 2.87 0.04
Black Subgroup
Gene/tSNP Genotype Groups OR 99% CI p-value
TGFβ1: rs4803455 AA vs. CC 0.39 0.06 - 2.61 0.20
CA vs. CC 3.04 0.56 - 16.33 0.09
TGFβ1:rs4803457 TT vs. CC 3.50 0.50 - 24.53 0.10
CT vs. CC 7.44 1.19 - 46.41 0.005
TGFβR1: rs10739778 CC vs. AA 0.19 0.02 - 2.08 0.07
AC vs. AA 0.24 0.05 - 1.09 0.02
  1. Abbreviations: tSNP, tagging single nucleotide polymorphism; OR, odds ratio; CI, confidence interval.
  2. a α set at 0.01 because of multiple testing.
  3. b SNP genotypes dichotomized (homozygote wildtype, homozygote variant + heterozygote) due to small homozygote variant frequencies in either cases, controls, or both.