Variation in endoglin pathway genes is associated with preeclampsia: a case–control candidate gene association study

Table 3 Black subgroup demographic and clinical characteristics

Variable	Cases (n = 30)	Controls (n = 30)	p-value
Maternal age, years (Mdn (min-max))	20.0 (14-37)	20.0 (14-37)	0.99^a
Gravida (Mdn (min-max))	1 (1-6)	1 (1-6)	0.38^a
Nulliparous (n, %)	25 (83.3%)	25 (83.3%)	-------
Gestational age at delivery, wks (Mdn (min-max))	36.9 (27.4-40.0)	40.6 (37.1-42.1)	< 0.001 ^a
Birthweight, grams (M (SD))	2313.9 (715.8)	3388.8 (405.3)	< 0.001 ^b
Avg. SBP < 20 weeks’, mm Hg (M (SD)) ^c	113.3 (9.2)	114.4 (6.8)	0.60^d
Avg. DBP < 20 weeks’, mm Hg (M (SD)) ^c	70.4 (6.5)	69.2 (4.2)	0.41^d
Avg. SBP in labor, mm Hg (M (SD)) ^e	159.9 (17.8)	120.7 (9.1)	< 0.001 ^b
Avg. DBP in labor, mm Hg (M (SD)) ^e	97.1 (10.4)	72.6 (7.4)	< 0.001 ^d
Pre-pregnancy BMI (Mdn (min-max)) ^f	23.0 (17.7-38.4)	25.8 (19.4-49.9)	0.25^a

Abbreviations: (Mdn (min-max)), median (minimum-maximum); wks, weeks; (M (SD)), mean (standard deviation); Avg. SBP, average systolic blood pressure; mmHg, millimeters of mercury; Avg. DBP, average diastolic blood pressure; BMI, body mass index.
^a Mann–Whitney U test.
^b Independent samples t-test with unequal variances.
^c n = 24 cases & n = 29 controls.
^d Independent samples t-test.
^e n = 30 cases & n = 29 controls.
^f n = 27 cases & n = 30 controls.

ISSN: 1471-2393