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Table 1 tSNPS examined in iPLEX® assays

From: Variation in endoglin pathway genes is associated with preeclampsia: a case–control candidate gene association study

Assay 1

Assay 2


rs numbers


rs numbers

Endoglin (ENG)

rs10987746, rs10819309, rs10760505, rs11792480, rs10121110


rs2043136, rs13075948, rs1346907, rs3773652, rs4955212, rs1155708, rs3773640, rs1036097, rs2082224, rs876688, rs744751, rs1078985, rs17025785, rs877572, rs5020833, rs6809777, rs6802220, rs9843942, rs6550005, rs3773644, rs3773645, rs13083813, rs12487185, rs13086588, rs6792117, rs3773663, rs4522809, rs11129420, rs995435, rs11924422

Transforming growth factor beta 1 (TGFβ1)

rs4803455, rs1800469, rs4803457, rs8179181, rs1800468, rs11466314

Transforming growth factor beta receptor 1 (TGFβR1)

rs6478974, rs420549, rs10739778

Activin receptor like kinase 1 (ALK1)

rs3759178, rs11169953, rs706819

Transforming growth factor beta receptor 2 (TGFβR2)

rs749794, rs3087465

  1. Note. The online Human GenoTyping Tools and MassARRAY® Assay Designer v4.0 software ( were used to design the iPLEX® assays. To optimize the multiplex reactions, tSNPs were grouped into Assay 1 or Assay 2.