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Table 7 Estimates of clinical impact

From: An integrative review of the side effects related to the use of magnesium sulfate for pre-eclampsia and eclampsia management

 

Affected patellar reflex

Respiratory depression

Skipped or delayed dose

Calcium gluconate use

Incidence amongst 9556 women

1.6%

1.3%

3.6%

0.18%

Number of pre-eclamptic/eclamptic women needed to treat to experience one incidence (i.e., number needed to harm)

61

77

27

555

Scenario: A hospital delivers 5000 women annually. Assuming a rate of PE/E of 5%, 250 women annually will require treatment with magnesium sulfate.

Frequency of 1 case (months)

2.9 months

3.7 months

1.3 months

26.7 months