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Table 2 Exclusion criteria

From: A multi-centre phase IIa clinical study of predictive testing for preeclampsia: improved pregnancy outcomes via early detection (IMPROvED)

Unsure of LMP and unwilling to have USS at ≤ 20 weeks

≥ 3 miscarriages

≥3 terminations

Known or suspected major fetal anomaly/abnormal karyotype

Essential hypertension treated pre-pregnancy

Moderate-severe hypertension at booking (BP >160/100 mmHg)


Renal disease

Systemic Lupus Erythematosus

Anti-phospholipid syndrome

Sickle cell disease

HIV positive

Major uterine anomaly

Cervical suture in situ

Knife cone biopsy

Long term steroids

Treatment with low-dose aspirin

Treatment with heparin/low molecular weight heparin