From: Potential prevention of small for gestational age in Australia: a population-based linkage study
Study variable | Preterm infant | Term infant, diabetic mother | Term infant, non-diabetic mother | |||
---|---|---|---|---|---|---|
Adjusted OR (95% CI) | Model-based PAF (95% CI) | Adjusted OR (95% CI) | Model-based PAF (95% CI) | Adjusted OR (95% CI) | Model-based PAF (95% CI) | |
Country of birth, Aboriginality | Â | Â | Â | Â | Â | Â |
  Aboriginal Australian | 1.08 [0.84, 1.39] | 0.36 [-0.92, 1.68] | 1.08 [0.75, 1.57] | 0.13 [-0.48, 0.80] | 1.29 [1.20, 1.38] | 0.87 [0.61, 1.12] |
  Non-Aboriginal Non-Australian†| 1.00 |  | 1.00 |  | 1.00 |  |
  Non-Australian | 1.67 [1.46, 1.90] | 11.41 [8.36, 14.41] | 1.92 [1.72, 2.14] | 27.01 [22.74, 31.23] | 1.54 [1.50, 1.59] | 11.08 [10.29, 11.86] |
ARIA+remoteness | Â | Â | Â | Â | Â | Â |
  Major cities | 0.88 [0.77, 1.01] |  | Not retained |  | Not retained |  |
  Inner regional†| 1.00 |  |  |  | ||
  Outer regional | 0.77 [0.60, 0.98] |  |  |  | ||
  Remote | 0.36 [0.17, 0.78] |  |  |  | ||
Socio-economic group | Â | Â | Â | Â | Â | Â |
  1st quintile (Most advantaged)†| (1st–4th quintiles vs. 5th quintile) | 1.00 |  | (1st–3rd quintiles vs. 4th, 5th quintile) |  | |
  2nd quintile | 1.15 [0.97, 1.35] |  | ||||
  3rd quintile | 1.06 [0.89, 1.26] |  | ||||
  4th quintile | 1.23 [1.02, 1.47] |  | 1.12 [1.08, 1.16] |  | ||
  5th quintile (Most disadvantaged) | 1.22 [1.07, 1.40] |  | 1.41 [1.21, 1.64] |  | 1.18 [1.15, 1.22] |  |
Inter-pregnancy interval | Â | Â | Â | Â | Â | Â |
  6–41 months, nulliparity†| Not retained |  | Not retained |  | 1.00 |  |
  <6 or ≥42 months |  |  | 1.14 [1.08, 1.19] |  | ||
Number of previous pregnancies | Â | Â | Â | Â | Â | Â |
  0 | 1.89 [1.62, 2.19] | 26.97 [21.25, 32.52] | 2.71 [2.38, 3.09] | 39.82 [35.22, 44.14] | 2.73 [2.62, 2.84] | 36.96 [35.80, 38.13] |
  1†| 1.00 |  | 0.66 [0.53, 0.83] |  | 1.00 |  |
  2 | 0.57 [0.45, 0.70] |  | 0.56 [0.41, 0.77] |  | 0.71 [0.67, 0.74] |  |
  3 | (0, 2+ vs. 1) |  | (0,2+ vs. 1) |  | 0.55 [0.51, 0.61] |  |
  4+ | 0.47 [0.41, 0.55] | |||||
Number of previous births by caesarean | Â | Â | Â | Â | Â | Â |
  0†| Not retained |  | Not retained |  | 1.00 |  |
  1 |  |  | 0.92 [0.87, 0.97] |  | ||
  2 |  |  | (None vs. Any) |  | ||
  3+ |  |  |  | |||
Number of previous preterm births | Â | Â | Â | Â | Â | Â |
  0†| Not retained |  | Not retained |  | 1.00 |  |
  1 |  |  | 1.68 [1.55, 1.82] | 1.17 [0.95, 1.38] | ||
  2+ |  |  | 2.00 [1.46, 2.72] | 0.11 [0.55, 0.17] | ||
Number of stillbirths | Â | Â | Â | Â | Â | Â |
  0 | Not retained |  | Not retained |  | 1.00 |  |
  1+ |  |  | 1.40 [1.14, 1.72] | 0.12 [0.04, 0.20] | ||
Number of previous SGA infants | Â | Â | Â | Â | Â | Â |
  0†| 1.00 |  | 1.00 |  | 1.00 |  |
  1 | 3.70 [3.02, 4.54] | 9.81 [8.00, 11.67] | 4.00 [3.28, 4.88] | 7.27 [5.91, 8.73] | 4.90 [4.67, 5.14] | 11.16 [10.73, 11.62] |
  2 | 7.56 [5.03, 11.36] | 3.11 [2.22, 4.13] | 8.93 [5.52, 14.42] | 1.44 [0.89, 2.06] | 12.27 [10.93, 13.77] | 2.24 [2.06, 2.43] |
  3+ | – |  | – |  | 16.89 [13.10, 21.78] | 0.54 [0.45, 0.65] |
Pre-existing/Gestational diabetes | 0.60 [0.49, 0.74] | Â | Not retained | Â | Not retained | Â |
Pregnancy hypertension | 4.46 [3.94, 5.05] | 28.80 [25.97, 31.64] | Not retained | Â | 1.17 [1.12, 1.22] | 1.22 [0.84, 1.89] |
Chronic hypertension | 3.12 [2.34, 4.16] | 2.73 [1.80, 3.78] | Not retained | Â | 1.31 [1.14, 1.50] | 0.20 [0.09, 0.32] |
Illicit drug use during pregnancy | 1.82 [1.29, 2.57] | 1.45 [0.52, 2.43] | 3.25 [1.46, 7.22] | 0.31 [0.04, 0.64] | 2.00 [1.74, 2.29] | 0.57 [0.44, 0.70] |
Smoking during pregnancy | 2.23 [1.91, 2.61] | 12.41 [9.79, 14.99] | 1.45 [1.21, 1.75] | 2.51 [1.14, 3.92] | 2.31 [2.22, 2.40] | 10.28 [9.77, 10.83] |
First antenatal care visit ≥14 weeks | Not retained |  | Not retained |  | 1.05 [1.01, 1.08] | 0.79 [0.20, 1.39] |
Fetus with congenital anomaly | 2.26 [1.86, 2.74] | Â | Not retained | Â | 1.46 [1.35, 1.59] | Â |