Table 3 Concentrations of placental growth factor, soluble vascular endothelial growth factor receptor-1 and their ratio in three different timepoints during pregnancy
From: Vasoactive agents for the prediction of early- and late-onset preeclampsia in a high-risk cohort
sFlt-1 pg/ml | ||||
|---|---|---|---|---|
Weeks + days of gestation | Early-onset preeclampsia | Late-onset preeclampsia | Controls with risk factors | Healthy controls |
12 + 0 to 14 + 0 | 1006.7 (715.0-1417.8) | 924.5 (760.3-1124.4) | 930.7 (803.2-1078.4) | 1020.0 (875.0-1189.0) |
18 + 0 to 20 + 0 | 1147.1 (592.2-2221.3) | 918.1 (772.9-1090.7) | 922.1 (743.4-1143.9) | 969.8 (831.8-1128.3) |
26 + 0 to 28 + 0 | 4847.3* (1318.6-17819.7) | 1054.4 (887.2-1252.9) | 1034.9 (876.2-1222.4) | 1141.3 (975.9-1334.8) |
PlGF pg/ml | ||||
Weeks + days of gestation | Early-onset preeclampsia | Late-onset preeclampsia | Controls with risk factors | Healthy controls |
12 + 0 to 13 + 6 | 29.4 (21.0-41.1) | 35.3 (30.3-41.3) | 37.9 (31.6-45.5) | 40.9 (35.3-47.3) |
18 + 0 to 20 + 0 | 71.9* (52.8-98.1) | 136.7 (112.7-165.8) | 132.4 (113.8-154.0) | 137.3 (120.9-155.9) |
26 + 0 to 28 + 0 | 44.6* (25.6-77.8) | 274.2 (222.4-338.1) | 271.5 ‡ (224.9-327.6) | 383.8 (332.3-443.3) |
sFlt-1/PlGF ratio | ||||
Weeks + days of gestation | Early-onset preeclampsia | Late-onset preeclampsia | Controls with risk factors | Healthy controls |
12 + 0 to 13 + 6 | 34.4 (22.2-53.3) | 26.6 (21.3-33.2) | 24.8 (19.7-30.5) | 25.0 (22.3-28.0) |
18 + 0 to 20 + 0 | 15.9 (6.6-38.8) | 6.7 (5.2-8.7) | 6.9 (5.3-8.9) | 7.1 (6.1-8.2) |
26 + 0 to 28 + 0 | 108.8* (40.5-292.1) | 4.0 (3.0-5.4) | 3.8 (3.0-4.9) | 3.0 (2.5-3.6) |