Effects of a ketogenic diet during pregnancy on embryonic growth in the mouse

Table 1 Body weight and blood metabolites of female SD and KD mice

		Weight	Glucose	Ketone	Cholesterol	Triglyceride	Num. of
		[gr]	[mmol/L]	[mmol/L]	[mmol/L]	[mmol/L]	embryos
Prior to	SD	29.5±0.5 (20)	6.4±0.3 (20)	0.25±0.02 (20)	3.4±0.2 (20)	2.1±0.2 (20)	-
Mating	KD	30.8±0.7 (20)	5.3±0.2 (20) *	1.94±0.15 (20) *	4.4±0.2 (17) *	1.8±0.1 (17) *	-
At E13.5	SD	45.0±1.3 (11)	7.0±0.5 (11)	0.22±0.04 (11)	2.8±0.1 (10)	2.8±0.2 (10)	12.9±0.6 (17)
	KD	45.4±1.2 (11)	6.6±0.5 (11)	1.57±0.23 (11) *	3.6±0.2 (11) *	5.1±1.1 (11) *	12.1±1.0 (12)
At E17.5	SD	67.1±1.7 (19)	5.9±0.3 (12)	0.27±0.04 (11)	2.0±0.1 (13)	2.7±0.3 (13)	10.9±1.2 (8)
	KD	58.9±1.1 (18) *	2.8±0.2 (11) *	3.96±0.30 (11) *	2.8±0.3 (12) *	7.8±1.8 (12) *	11.3±0.6 (6)
p-value	Diet	0.0094	< 0.0001	< 0.0001	< 0.0001	0.0569	–
	Time-pt	< 0.0001	0.0055	0.0001	< 0.0001	0.0011	–
	Interaction	0.0008	0.0411	0.0001	0.0273	0.0481	–

Values were measured just prior to mating, at E13.5 and at E17.5 (Mean ± SEM (Number of dams tested)). Statistically significant KD vs. SD p-values are indicated by a (*) for comparison at each time point.

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