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Table 2 Comparison of all collected data between neonates with and without sepsis (univariate analysis)

From: Risk factors and prognosis for neonatal sepsis in southeastern Mexico: analysis of a four-year historic cohort follow-up

Variable With sepsis Without sepsis P
  N = 514 (%) N = 11276 (%)  
Neonate-related
Gender (feminine/masculine) 233/281 5542/5732 0.22
Gestational age (wk)* 34 ± 4.3 39 ± 2.3 <0.0001
Birth weight (g)* 2069 ± 837 3053 ± 576 <0.0001
Height (cm)* 43.4 ± 5.9 49.3 ± 3.3 <0.0001
Premature (≤37 wks) 350 (68.1) 1581 (14.0) <0.0001
Postmature (≥42 wks) 5 (1.0) 131 (1.2) 0.45
Product of multiple pregnancy 41 (8.0) 204 (1.8) <0.0001
Abnormal umbilical cord 131 (25.5) 1620 (14.4) <0.0001
With perinatal asphyxia 17 (3.3) 81 (0.7) <0.0001
With intrauterine hypoxia 10 (1.9) 71 (0.6) 0.003
Apgar score ≤5 274 (53.3) 1,765 (15.7) <0.0001
With fetal distress 86 (16.7) 896 (7.9) <0.0001
Maternal-related
Age (yrs)* 26 ± 5.5 25 ± 5.4 0.10
Low educative level 284 (55.3) 6341 (56.2) 0.341
Gestations* 2 ± 1.2 2 ± 1.1 0.01
Deliveries* 0.5 ± 0.9 0.6 ± 0.9 0.001
Non-adequate pregnancy control 258 (50.2) 4112 (36.5) <0.0001
Experienced threat of abortion during this pregnancy 139 (27.0) 1905 (16.9) <0.0001
Abnormal placenta 86 (16.7) 436 (3.9) <0.0001
Dystocic delivery 151 (24.9) 5900 (52.3) <0.0001
Cesarean section 359 (69.8) 5232 (46.4) <0.0001
Abnormal amniotic fluid 159 (30.9) 1687 (15.0) <0.0001
Premature membrane rapture > 12 h 168 (32.7) 469 (4.2) <0.0001
Premature membrane rapture > 24 h 137 (26.7) 222 (2.0) <0.0001
Premature membrane rapture > 48 h 85 (26.7) 105 (0.9) <0.0001
Amnionitis 4 (0.8) 32 (0.3) 0.074
Preeclampsia ≤35 gestational wks 28 (5.4) 340 (3.0) <0.0001
Preeclampsia >35 gestational wks 26 (5.1) 569 (5.0) 0.530
Metabolic disease ≤35 gestational wks 27 (5.3) 326 (2.9) 0.002
Metabolic disease >35 gestational wks 26 (5.1) 343 (3.0) 0.007
Infectious disease ≤35 gestational wks 164 (31.9) 2793 (24.8) <0.0001
Infectious disease >35 gestational wks 79 (15.4) 1270 (11.3) 0.003
Clinical-course and medical-care related
Reanimation required 339 (66.0) 3888 (34.5) <0.0001
Mechanical ventilation required 160 (31.1) 209 (1.9) <0.0001
O2 inspiration fraction required > 60% 95 (18.5) 96 (0.9) <0.0001
Continuous positive airway pressure required 24 (4.7) 14 (0.01) <0.0001
Surfactant administration 49 (9.5) 34 (0.3) <0.0001
Respiratory complication 35 (6.8) 91 (0.8) <0.0001
Intraventricular bleeding 20 (3.9) 28 (0.2) <0.0001
Surgical procedure required 14 (2.7) 10 (0.1) <0.0001
Medical procedure required 293 (57.0) 609 (5.4) <0.0001
  1. *Mean ± Standard deviation (SD).